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ST13 PAT5C6AT Monoclonal Antibody [PAT5C6AT] (CPAB0290)

SKU:
CPAB0290
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT5C6AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet
Product Name:ST13 PAT5C6AT Antibody
Product Sku:CPAB0290
Size:5μg
Host Species:Mouse
Immunogen:Anti-human ST13 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ST13 protein 1-369 amino acids purified from Ecoli.
Clone:PAT5C6AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:ST13 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a
Background:ST13 is an adaptor protein (co-chaperone) that mediates the association of HSP70 & HSP90 and appears in early receptor complexes. ST13 plays a role in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of ST13 is downregulated in colorectal carcinoma tissue signifying that is candidate tumor suppressor gene. Through common binding to both Hsp70 and Hsp90, ST13 functions as an adaptor that can integrate Hsp70 and Hsp90 interactions. The expression of ST13 decreases in colorectal cancer tissue compared with that in adjacent normal tissue. ST13 is mostly expressed in colorectal epithelia and adenocarcinoma cells. ST13 functions to promote the efficiency of glucocorticoid receptor maturation in cells. The expression levels of the ST13 gene were significantly decreased in primary tumors compared with adjacent mucosa.
Synonyms:AAG2, SNC6, HSPABP, FAM10A1, FAM10A4, HSPABP1, ST-13, Hsc70-interacting protein, Suppression of tumorigenicity protein 13, Putative tumor suppressor ST13, Protein FAM10A1, Progesterone receptor-associated p48 protein, Renal carcinoma antigen NY-REN-33, ST13, HIP, HOP, P48, PRO0786, FLJ27260, MGC129952.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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