2'-O-methylcytidine/ Cm Monoclonal Antibody (CAB20693)
The 2'-O-methylcytidine/ Cm Monoclonal Antibody (CAB20693) is a high-quality antibody developed for reliable detection and analysis of target proteins. RNA methylation plays a significant regulatory role in various of physiological activities. 2'-O-methylcytidine (Cm) is one of the representative 2'-O-methylation and base-methylation modified epigenetic marks of RNA. 2'-O-Methylcytidine is derivative of the nucleoside residue cytidine with a methyl group attached to the 2'-oxygen position. 2’-O-methylcytidine was found to be related to various diseases including cancer, and it might have great potential to be novel biomarkers for detection of breast cancer in the early stage. In addition, 2'-O-methylcytidine showed as an inhibitor of RNA polymerase from the hepatitis C virus (HCV). And 2’-O-methylcytidine was involved in plant stress responses. RRID Gene ID Swiss Prot Synonym Cm; 2'-O-methylcytidine; 2'-O-methylcytidine/ Cm
This antibody is validated for use in ELISA, DB applications and has demonstrated reactivity against Species independent samples.
Product Name:
2'-O-methylcytidine/ Cm Monoclonal Antibody
SKU:
CAB20693
Size:
100μL, 20μL
Reactivity:
Species independent
Clone Number:
ARC50639
Conjugate:
Unconjugated
Immunogen:
Chemical compounds corresponding to 2'-O-methylcytidine/ Cm.
Tested Applications:
ELISADB
Recommended Dilution:
DB
1:500 - 1:2000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
Cm, 2'-O-methylcytidine, 2'-O-methylcytidine/ Cm
Positive Sample:
-
Cellular Localization:
-
Calculated MW:
-
Observed MW:
Refer to figures
RNA methylation plays a significant regulatory role in various of physiological activities. 2'-O-methylcytidine (Cm) is one of the representative 2'-O-methylation and base-methylation modified epigenetic marks of RNA. 2'-O-Methylcytidine is derivative of the nucleoside residue cytidine with a methyl group attached to the 2'-oxygen position. 2’-O-methylcytidine was found to be related to various diseases including cancer, and it might have great potential to be novel biomarkers for detection of breast cancer in the early stage. In addition, 2'-O-methylcytidine showed as an inhibitor of RNA polymerase from the hepatitis C virus (HCV). And 2’-O-methylcytidine was involved in plant stress responses. RRID Gene ID Swiss Prot Synonym Cm; 2'-O-methylcytidine; 2'-O-methylcytidine/ Cm
Purification Method:
Affinity purification
Gene ID:
-
RRID:
-
Buffer Information:
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
The 2'-O-methylcytidine(Cm) Rabbit mAb (CAB20693) are tested in Dot Blot against 2'-O-methylcytidine and unmodified cytidine.2'-O-methylcytidine ：Biotin-5'CGATAACCACTAGT(Cm)3'unmodified cytosine：Biotin-5'CGATAACCACTAGTC3'
