Cystatin C is a member of family 2 of the cystatin superfamily. It is found in the majority of human tissues and bodily fluids, and it serves as a biomarker for kidney function. Cystatin C inhibits several cysteine proteases, including papain and Cathepsins B; H; K; L, as well as S. Cystatin C inhibits cysteine proteinases, and it has been postulated that this proteinase regulator plays a significant physiological function as a local modulator of enzyme activity. It has been investigated for its potential value in predicting new-onset or worsening heart disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition); such as Alzheimer's disease. Human Cystatin C/CST3 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Human Cystatin C/CST3 Recombinant Protein (RPES1661)
Recombinant Human Cystatin C is produced by our Mammalian expression system and the target gene encoding Ser27-Ala146 is expressed.
> 95 % as determined by reducing SDS-PAGE.
AP Mol Mass:
Lyophilized from a 0.2 µm filtered solution of 10mM PB; 200mM Nacl; pH6.5.
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.