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ATP1B1 Rabbit Polyclonal Antibody (CAB12403)

SKU:
CAB12403
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 3 Anti-ATP1B1 Antibody CAB12403
  • Cell Biology Antibodies 3 Anti-ATP1B1 Antibody CAB12403
  • Cell Biology Antibodies 3 Anti-ATP1B1 Antibody CAB12403
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ATP1B1 Rabbit Polyclonal Antibody
SKU:CAB12403
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 65-240 of human ATP1B1 (NP_001668.1).
Sequence:KPTY QDRV APPG LTQI PQIQ KTEI SFRP NDPK SYEA YVLN IVRF LEKY KDSA QRDD MIFE DCGD VPSE PKER GDFN HERG ERKV CRFK LEWL GNCS GLND ETYG YKEG KPCI IIKL NRVL GFKP KPPK NESL ETYP VMKY NPNV LPVQ CTGK RDED KDKV GNVE YFGL GNSP GFPL
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200
Synonyms:ATP1B; ATP1B1
Positive Sample:U-251MG,Mouse brain,Mouse liver,Mouse kidney,Rat kidney,Rat brain
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Single-pass type II membrane protein.
Calculated MW:35kDa
Observed MW:50kDa

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known.

Purification Method:Affinity purification
Gene ID:481
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using ATP1B1 Rabbit pAb (CAB12403) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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