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    p38 MAPK Signaling Review(Post)

    The p38 MAPK signaling pathway is an intracellular signaling pathway that plays a crucial role in cellular responses to various stressors and inflammatory stimuli. It is a part of the larger MAPK ...

    MAPK Signaling: Unraveling the Pathway of Mitogen Stimulation(Post)

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    Interferons(Post)

    Interferons (IFNs) are a group of signalling proteins that are produced and released from cells in response to viral infection and other stimuli such as normal and tumour cell survival and ...

    MAPK Oxidative Stress Pathway: A Journey through Cellular Signaling(Post)

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    MAPK Signaling in Inflammatory Cytokines Pathways(Post)

    The Mitogen-Activated Protein Kinase (MAPK) pathway is a pivotal signaling cascade that plays a crucial role in mediating cellular responses to various external stimuli. This pathway is intricate ...

    How to Thaw Cells: Best Practices for Cell Culture Success(Post)

    Cell culture techniques are fundamental to biomedical research, providing crucial insights into cellular functions, drug discovery, and disease mechanisms. A critical step in cell culture is the ...

    Fenofibrate Usage for Diabetes Damage(Post)

    Fenofibrate, also known as FEN, is a drug that is used to lower cholesterol levels. It works by blocking the absorption of dietary cholesterol in the small intestine and therefore, re ...

    Boiling Proteins for Western Blotting: Optimal Conditions and Best Practices(Post)

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    NLRP3 Inflammasome & Cytokine Secretion(Post)

    Nod-like receptors Nod like receptors (NLRs) are a versatile family of relatively recently discovered intracellular receptors which have a b ...

    Decoding the Language of Cells: Chemokine Signaling Pathways Unveiled(Post)

    Chemokines are small signaling proteins that play a crucial role in the immune system by directing the movement of cells, orchestrating immune responses, and maintaining tissue homeostasis. Th ...

    VEGF: Inflammation and Tumourigenesis(Post)

    What is VEGF? Vascular Endothelial Growth Factors (VEGFs) are a group of homodimeric polypeptides, and are master regulators of vascular development, maintenance and ...

    The role of IL-18 in health and disease(Post)

    Exploring IL-18: A key cytokine in inflammation and disease. Key Takeaways: IL-18, a pro-inflammatory cytokine, plays a pivotal role in immune responses, particularly in inducing Type II ...

    What I learnt from meeting 1000+ researchers(Post)

    Over the past few years I have traversed through academia in a few different guises, first as a PhD student for about 5 years, then onto the traditional route of a post-doc, followed by a sale ...

    OKRs for Researchers(Post)

    Objectives & Key Results Objectives & Key Results (OKRs) is a framework for setting and tracking goals. At Assay Genie, we've tailored this approach to sui ...

    Keep your Lab Book up to Date(Post)

    When PhDs and Post-Docs start in new lab they have the best intentions to keep their lab books up to date with notes, new research methods, data, and protocol information. These best efforts u ...

    COVID-19 Workplace Testing(Post)

    Workplace Testing for COVID-19 Corporate Testing for COVID-19 The impact of COVID-19 on the econo ...

    How to improve your relationship with your PI or Professor(Post)

    After probably a round or two of interviews and a PhD in your pocket you would think that proving yourself in your new lab would not be an issue. After all, they did hire you because you were ...

    Converting RPM to G-force in Centrifugation(Post)

    Centrifuges play a pivotal role in scientific research and various industries, enabling efficient separation and isolation of components within a sample. Understanding the relations ...

    Scicomm (Science Communication) tips for beginners! (Post)

    Science communication (Scicomm) is currently on the up. As rebellion against the increasing distrust of science stemmed from bigoted and ignorant leaders, scientists are turning to ...

    Networking tips for scientists(Post)

    During my PhD I knew how networking was important, it helped me source reagents off other labs, get the best advice and helped me land a post doc at Cambridge University. Its not ...

    CV writing tips for scientists(Post)

    Making the switch! This article provides some help on CV writing tips for scientists for PhDs and PostDocs looking for jobs outside of academia and what they might need to ...

    Bullying in the Laboratory and workplace(Post)

    The lab can be one of the greatest places in the world to make live long friends. Spending countless hours in a tissue culture room late into the middle of the night, sharing similar frustrati ...

    ST2 and IL33(Post)

    ST2, a member of the IL-1R Subfamily ST2 is a member of the IL-1R subfamily and was identified in 1989 [1]. The ST2 gene is located on chromos ...

    A Quick Guide to Myelin(Post)

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    Freezing Stimulated T Cells: A Detailed Guide(Post)

    Cryopreservation of stimulated T cells is a common technique in immunology research, allowing for long-term storage while maintaining their functional viability. Stimulated T cells—espec ...

    Tigatuzumab: Advancing Cancer Research with Targeted Therapies(Post)

    Quick Facts About TigatuzumabWhat is Tigatuzumab?Tigatuzumab is a monoclonal antibody that targets the death receptor 5 (DR5) pathway, inducing apoptosis in cancer cells.What is the mec ...

    Fibroblast Markers(Post)

    Fibroblasts, essential components of connective tissues, play vital roles in maintaining tissue structure and function. Their remarkable ability to produce and organize the extracellular matrix ...

    Hybridoma Technology: Revolutionizing Antibody Production(Post)

    Immunology · Antibody ProductionHybridoma Technology: How Monoclonal Antibodies Are MadeHybridoma technology, pioneered by Georges Köhler and César Milstein in 1975, is the method that made monoclona ...

    Data Science for Immunologists | Assay Genie(Post)

    By Dr. Niclas Thomas “Data science” is a recent addition to the vocabulary of analytics, and can mean many different things to different people. As f ...

    HMGB1 in inflammation and cancer(Post)

    HMGB1 Functional Overview High mobility group box 1 ( HMGB1), a member of the high-mobility group (HMG) family, was first identified in the thymus in 1973 a ...

    Beyond Burnout: How T Cell Exhaustion Hijacks Cancer Immunity and What We Can Do About It(Post)

    Imagine a highly trained soldier, elite and effective, sent to the front lines of a relentless war. Day after day, they fight without rest, their supplies dwindle, and the enemy never stops coming. E ...

    Ferroptosis: A New Frontier in Cancer Therapy(Post)

    For decades, the primary strategy in cancer treatment has been to trigger apoptosis, a form of programmed cell death, in malignant cells. However, many cancers develop resistance to apoptosis-induci ...

    Transformation Protocol – Sample Transformation Protocols(Post)

    Introduction Transformation of bacteria with plasmids is not only of note for bacterial studies but also can be used for gene expression studies in mammalian cells. Most plasmids are of bac ...

    SLAMF7: Activating Natural Killer Cells for Potent Anti-Cancer Responses(Post)

    Introduction to SLAMF7 in Cancer Immunotherapy SLAMF7, also known as Signaling Lymphocytic Activation Molecule F7, is a surface receptor found on natural killer (NK) cells, T cells, ...

    Histamine Receptors: Gatekeepers of Immunological and Neurological Responses(Post)

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    Introducing BioSymposia: The Gathering Place for Science(Post)

    Announcement · Powered by Assay GenieIntroducing BioSymposia: The Gathering Place for ScienceWe’re excited to announce the launch of BioSymposia, our new sister platform and a free home for sc ...

    The Powerhouse of Immunity: How Mitochondrial Fitness Fuels the Fight Against Cancer(Post)

    Why do powerful cancer immunotherapies work wonders for some patients but fail for others? The answer may lie not just in the cancer cells themselves, but in the energy levels of our own immune warri ...

    Christmas Lab Party Competition | Assay Genie(Post)

    We know it gets tiring being in the lab every day, especially with the evenings getting darker and gloomier. So, to get you in the festive spirit, we're holding a competition to win money to t ...

    Cortisol and the Immune Response(Post)

    Endocrinology · ImmunologyCortisol and the Immune ResponseCortisol is the body’s primary stress hormone — a glucocorticoid released by the adrenal gland that powerfully shapes the immune system. Acti ...

    Biofilms: The Bacteria Invaders You Can't Ignore(Post)

    If you've ever had a urinary tract infection, you know all about bacteria. These tiny organisms can invade your body and cause all sorts of problems. But what you may not know is th ...

    Metabolism or pluripotency – which regulates which? A chicken or the egg story.(Post)

    By Sophie Arthur How many diseases and conditions do you think exist in this world? Thousands? Hundreds of thousands? Maybe even millions? Unfortunately, I don’t know the answer. But what ...

    How to Choose a Secondary Antibody(Post)

    The selection of a secondary antibody is a critical step in the experimental design of various immunodetection methods, including Western Blot, ELISA, immunohistochemistry (IHC), and immunofluore ...

    Avizakimab: Unveiling the Role of Anti-CD47 in Cancer Research(Post)

    Quick Facts About AvizakimabWhat is Avizakimab?Avizakimab is a monoclonal antibody designed to target the CD47 protein, a key checkpoint in immune regulation, particularly in cancer the ...

    ​TNF alpha & Inflammation(Post)

    Immunology · Cytokine SignallingTNF-alpha and Inflammation: Structure, Signalling & TherapyTumour necrosis factor alpha (TNF-α) is one of the most important pro-inflammatory cytokines in the body ...

    OX40 Agonists: Revitalizing the Immune Response in Cancer(Post)

    Cancer immunotherapy has revolutionized treatment options, offering strategies to harness the immune system to target and destroy tumors. One emerging area of interest is the use of OX40 ...

    8 Steps to Mindfulness in the Laboratory(Post)

    Stress and anxiety are a normal part of our daily lives and impact everything we do from our relationships with loved ones to our performance in the laboratory. Like any scientist, I experienced ...

    29 PhD Thesis Writing Tips(Post)

    Explore 29 essential tips for crafting a compelling and well-structured PhD thesis, blending effective writing practices with time management and academic rigor for a successful dissertation jour ...

    Department of Oncology Retreat 2025(Post)

    Department of Oncology RetreatAssay Genie was honoured to sponsor and participate in the inaugural 2025 Department of Oncology Retreat, hosted by the University of Lausanne and Lausanne ...

    Programmable Synthetic Hybrid Receptors (Hybrid-Rs): The Next Generation of Precision Immunotherapy(Post)

    Imagine a world where cancer treatment is no longer a blunt instrument but a precision-guided surgical strike, executed by the body's own immune system. For years, we have dreamed of 'smart' cells t ...

    Passaging Hybridoma Cells: A Detailed Guide(Post)

    Hybridoma cells are essential tools for producing monoclonal antibodies and are derived by fusing B lymphocytes (antibody-producing cells) with myeloma cells (cancer cells) to achieve bo ...

    Choosing a Fluorescent Protein: A Comprehensive Guide (Post)

    Fluorescent proteins (FPs) have revolutionized the field of molecular and cellular biology, allowing scientists to visualize and track biological processes in live cells with unprecedented clarit ...

    10 reasons why you should do a science outreach event(Post)

    I'll start this post off with a story. When I was half way through my PhD and I had found my passion for science communication, I approached my supervisor for the first time to ask “Can I h ...

    What is RNAi? All You Need to Know(Post)

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    Multiple Sclerosis and Stem Cells(Post)

    By Sonika Singh PhD candidate, University of Nottingham A Devastating Disease Multiple Sclerosis (MS) is a chronic and inflammatory disease ba ...

    Transduction vs Transfection: Understanding Gene Delivery Techniques(Post)

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    Western Blot Training: A Comprehensive Guide(Post)

    Western blotting, a cornerstone technique in molecular biology, biochemistry, and immunogenetics, is pivotal for detecting specific proteins in a sample. Its applications span various scientific ...

    Prostate Cancer Markers : What to Look for in Your Test Results(Post)

    In this blog post, we will review prostate cancer markers and what you should look for in your results. Prostate antigen marker (PSA) and p63 are the most common markers found in pr ...

    How to be a Confident Speaker (Scientific)(Post)

    Like needles in a haystack, interesting speakers that bring charisma and rock n roll to their talks are hard to come by. No matter what the research interests of the audience, these speakers h ...

    Tezepelumab: A Breakthrough in Severe Asthma Treatment and Research(Post)

    Quick Facts About TezepelumabWhat is Tezepelumab?Tezepelumab is a monoclonal antibody designed to inhibit thymic stromal lymphopoietin (TSLP), a key driver of airway inflammation in sev ...

    How do Neurons work?(Post)

    A neuron is a cell that processes and transmits information through electrical and chemical signals. There are trillions of them in the human brain, which is able to carry out so many comple ...

    Validation of MycoGenie Rapid Mycoplasma Detection Kit - A highly sensitive visual determination method for Mycoplasma detection.(Post)

    The MycoGenie Rapid Mycoplasma Detection Kit enables the detection of 28 Mycoplasma species in under 1 hour using a simple visual determination method, eliminating the need for expensiv ...

    Tidutamab: Unlocking the Potential of SSTR2-Targeting in Oncology Research(Post)

    Quick Facts About TidutamabWhat is Tidutamab?Tidutamab is a monoclonal antibody designed to target somatostatin receptor 2 (SSTR2), a key protein involved in various neuroendocrine tumo ...

    Lusvertikimab: Unveiling the Potential in Immuno-Oncology(Post)

    What You Need to Know About LusvertikimabWhat is Lusvertikimab?Lusvertikimab is a monoclonal antibody designed to inhibit the IL-4 receptor, a key player in regulating immune responses, ...

    Ras signaling pathway(Post)

    A wide variety of cell surface receptors activate Ras GTPase, including the tyrosine receptor linked to the epidermal growth factor receptor (EGFR) (Wells 1999). Upon receptor stimulation, son ...

    Barrett’s Oesophagus to Oesophageal Adenocarcinoma – Review(Post)

    Oesophageal Adenocarcinoma is on the rise globally affecting more than 450,000 people worldwide (Pennathur, Gibson et al. 2013). Once diagnosed overall 5-year survival ranges from 15 % to ...

    COVID-19 Antibody Testing(Post)

    COVID-19 Antibody Testing Antibody Production in COVID-19 COVID-19, the novel coronavirus disease ...

    Next-Generation Cancer Therapy: Harnessing CAR-T Cells and the Tumor Microenvironment(Post)

    For decades, the fight against cancer has been a relentless battle of attrition, often with treatments that harm the body as much as the disease. But a new era of precision medicine is dawning, one t ...

    Navigating Cell Culture Supplements: Fetal Bovine Serum vs. Horse Serum in Biomedical Research(Post)

    The choice of appropriate cell culture supplements emerges as a crucial factor in ensuring the efficacy and consistency of experimental results. Among the various options available, two common ...

    Bersanlimab: Revolutionizing Cancer Research with Anti-CD47 Therapeutics(Post)

    What You Need to Know About BersanlimabWhat is Bersanlimab?Bersanlimab is a cutting-edge anti-CD47 monoclonal antibody designed to disrupt cancer cells' evasion of immune detection.What ...

    Biological Role of GLP-1(Post)

    Glucagon-like peptide-1 (GLP-1) is a critical hormone in the regulation of glucose metabolism and has garnered significant attention due to its therapeutic potential in managing diabetes ...

    4-1BB: Energizing Immune Cells to Overcome Tumor Resistance(Post)

    Immunotherapy has become a central pillar in the fight against cancer, with a focus on enhancing the body’s natural defenses. Among the molecules at the forefront of immunotherapeutic re ...

    Cancer & Tumour Suppressors – Mini Review(Post)

    Cancer DevelopmentCancer is a group of diseases that involves abnormal cell growth resulting in malignant tumours/ malignant neoplasms. Cancer is a leading cause of morbidity, with 14 million n ...

    3D Organoid Cell Viability Assay: Performance Assessment in Human Colon Organoids(Post)

    The 3D Organoid Cell Viability Assay (AKES081) demonstrated high sensitivity and low cytotoxicity, making it ideal for long incubation studies (24-48 hours) and high-throughput applicat ...

    Amatuximab: Exploring Mesothelin-Targeted Therapy for Cancer Research(Post)

    What You Need to Know About AmatuximabIs Amatuximab safe?Amatuximab has shown a manageable safety profile in clinical trials, with most side effects being mild to moderate. Severe adver ...

    AACR 2025(Post)

    Assay Genie attended AACR 2025 in ChicagoSean, Shane and David had a great few days in Chicago discussing research with scientists from across the globe at the Assay Genie booth. " ...

    Pyroptosis: A Promising Target for Immunotherapy(Post)

    Pyroptosis is an immunogenic form of cell death, meaning that it triggers an immune response. This makes pyroptosis a potentially promising target for immunotherapies that aim to bo ...

    Enavatuzumab: Revolutionizing Cancer Research Through Novel Therapeutics(Post)

    Quick Facts About EnavatuzumabWhat is Enavatuzumab?Enavatuzumab is a monoclonal antibody targeting the TWEAK receptor (Fn14), pivotal in tumor growth and immune regulation.What is the m ...

    Mouse Injection Guide: Intraperitoneal, Subcutaneous, Intramuscular & Intravenous Routes(Post)

    In Vivo Methods · ProtocolsMouse Injection Guide: Intraperitoneal, Subcutaneous, Intramuscular & Intravenous RoutesRoute choice and injection technique determine how much of a dose actually reach ...

    Mesenchymal Stem Cells: Navigating the Frontiers of Regenerative Medicine(Post)

    Mesenchymal stem cells (MSCs) have emerged as pivotal players in the realm of regenerative medicine due to their unique properties and versatile potential. Originally discovered in the bone marro ...

    Monalizumab: A Breakthrough in Cancer Immunotherapy Targeting NKG2A(Post)

    Quick Facts About MonalizumabWhat is Monalizumab?Monalizumab is a first-in-class immune checkpoint inhibitor targeting NKG2A, developed to enhance anti-tumor immune response by blocking ...

    Codrituzumab: Unveiling Its Role in Cancer Research and Treatment(Post)

    What You Need to Know About CodrituzumabWhat is Codrituzumab?Codrituzumab is an investigational monoclonal antibody targeting CD47, an immune checkpoint that regulates immune responses ...

    The Notch Signalling Pathway: Its Steps and Impacts(Post)

    Notch signalling pathway review The Notch signalling pathway is a highly conserved intercellular signalling pathway that regulates various cellular processes. The Notch receptor is a t ...

    Icrucumab: Exploring the Role of Anti-Angiogenic Therapy in Cancer Research(Post)

    Quick Facts About IcrucumabWhat is Icrucumab?Icrucumab is a monoclonal antibody that targets vascular endothelial growth factor receptor-1 (VEGFR-1) to inhibit tumor angiogenesis.How Do ...

    Denosumab: A Comprehensive Overview of Mechanism, Applications, and Research Advances(Post)

    What You Need to Know About DenosumabWhat is Denosumab?Denosumab is a monoclonal antibody used primarily to treat osteoporosis and bone-related complications in cancer patients. It targ ...

    10 Steps to increase lab productivity(Post)

    How to increase lab productivityWhen you look back at some weeks in the lab it seems like you have achieved nothing and your lab productivity can be low. Your cloning hasn’t worked or your mice ...

    Mouse Monoclonal Antibody(Post)

    Mouse monoclonal antibodies are a valuable tool in the biomedical field. They can be used for a variety of applications, from research to clinical diagnostics. In this blog post, we ...

    #LabChats with Laura Menke(Post)

    At ELISA Genie we are hugely interested in the future of science and we feel that PhD students are at the heart of this. Our new series, #LabChats, will see us interview different scient ...

    TGF-β/SMAD signalling(Page)

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    Cell-Based ELISA Kits (Page)

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    Assay Genie Mission(Page)

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    Anti-Corruption Policy(Page)

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    Citations(Page)

    Product CitationsMore than 1,000 cited products in scientific journalsWe're not just any scientific company; our products have made waves in the scientific community. From groundbreaking ...

    Tunel 1-Step Assay Kits(Page)

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    Antibodies(Page)

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    Custom ELISA Kits(Page)

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    Immunohistochemistry (IHC) Buffers & Recipes(Page)

    What is IHC? Immunohistochemistry (IHC) is a valuable tool used for the identification of specific antigens within embedded tissue prepara ...

    Loading Control Antibodies(Page)

    Loading Control Antibodies | GAPDH, \u03b2-Actin & Tubulin | Assay Genie{"@context":"https://schema.org","@graph":[{"@type":"CollectionPage","@id":"%%GLOBAL_ShopPathSSL%%/loading-control-antibodi ...

    Resources(Page)

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    cGAS-STING cytosolic DNA sensing(Page)

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