Blog

Research Pulse · Data study Where biology is heading: what PubMed and 300,000 researcher visits reveal We compared five years of PubMed publication counts with two years of researcher visits to Assay Genie product pages. The result is a map of the research fields that are growing fastest, and the ones that are fading. See the breakout fields → 47×growth in lactylation papers since 2021 22×growth in p-tau217 papers since 2021 1.7Mnew PubMed papers in 2025 302kresearcher visits analysed Key Takeaways PubMed grew about 10% between 2021 and 2025, but protein lactylation papers grew 47-fold and p-tau217 papers grew 22-fold. GLP-1 drug research grew six-fold and ferr …

In the intricate landscape of the brain, cells constantly communicate, sending and receiving messages that govern our thoughts, memories, and movements. For decades, scientists believed this communication occurred primarily through direct synaptic connections. However, a new paradigm is emerging, centered on tiny messengers called extracellular vesicles (EVs). These microscopic packages, once dismissed as cellular debris, are now understood to be critical players in both health and disease. Groundbreaking research reveals that EVs facilitate the spreading of Lewy pathology between the peripheral and central nervous systems, fundamentally changing our understanding of how neurodegenerative di …

PD-L1 in Cancer Immunotherapy: Insights from Recent ResearchRecent advancements in cancer immunotherapy have underscored the critical role of programmed death-ligand 1 (PD-L1) in mediating immune evasion by tumors. This article delves into how PD-L1 expression influences T-cell mediated immune evasion in cancer, contributing to improved biomarker targeting for immunotherapy. By exploring the molecular mechanisms, clinical implications, and future directions of PD-L1 research, we aim to provide a comprehensive understanding of its significance in the evolving landscape of cancer treatment.Introduction to PD-L1PD-L1, a protein expressed on the surface of various cells, plays a pivotal role in …

The Role of CD25+FOXP3+CD45RA- Treg Cells in Cancer PrognosisIntroductionRegulatory T-cells (Treg cells) are a specialized subset of T-cells that play a pivotal role in maintaining immune homeostasis and tolerance. These cells are essential for preventing autoimmune diseases and controlling excessive immune responses. However, in the context of cancer, Treg cells have garnered significant attention due to their dual roles in promoting tumor angiogenesis and modulating antitumor immunity. This article delves into the prognostic significance of CD25+FOXP3+CD45RA- Treg cell infiltration in tumor specimens, highlighting their potential as biomarkers for cancer outcomes.Study SummaryIn a comprehe …