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Anti-CD164 Antibody (CAB17030)

SKU:
CAB17030
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
€129 - €259
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Description

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Antibody Name:Anti-CD164 Antibody
Antibody SKU:CAB17030
Antibody Size:20uL, 50 uL
Application:IHC
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-162 of human CD164 (NP_006007.2).
Application:IHC
Recommended Dilution:IHC 1:50 - 1:200
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-162 of human CD164 (NP_006007.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:DKNT TQHP NVTT LAPI SNVT SAPV TSLP LVTT PAPE TCEG RNSC VSCF NVSV VNTT CFWI ECKD ESYC SHNS TVSD CQVG NTTD FCSV STAT PVPT ANST AKPT VQPS PSTT SKTV TTSG TTNN TVTP TSQP VRKS TFD
Gene ID:8763
Uniprot:Q04900
Cellular Location:
Calculated MW:16kDa/19kDa/20kDa
Observed MW:Refer to figures
Synonyms:CD164, DFNA66, MGC-24, MGC-24v, MUC-24, endolyn
Background:This gene encodes a transmembrane sialomucin and cell adhesion molecule that regulates the proliferation, adhesion and migration of hematopoietic progenitor cells. The encoded protein also interacts with the C-X-C chemokine receptor type 4 and may regulate muscle development. Elevated expression of this gene has been observed in human patients with Sezary syndrome, a type of blood cancer, and a mutation in this gene may be associated with impaired hearing.
UniProt Protein Function:Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34+ cells to the stroma and by negatively regulating CD34+CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes.
NCBI Summary:This gene encodes a transmembrane sialomucin and cell adhesion molecule that regulates the proliferation, adhesion and migration of hematopoietic progenitor cells. The encoded protein also interacts with the C-X-C chemokine receptor type 4 and may regulate muscle development. Elevated expression of this gene has been observed in human patients with Sezary syndrome, a type of blood cancer, and a mutation in this gene may be associated with impaired hearing. [provided by RefSeq, Oct 2016]
UniProt Code:Q04900
NCBI GenInfo Identifier:257051036
NCBI Gene ID:8763
NCBI Accession:Q04900.2
UniProt Related Accession:Q04900
Molecular Weight:16kDa; 19kDa; 20kDa
NCBI Full Name:Sialomucin core protein 24
NCBI Synonym Full Names:CD164 molecule
NCBI Official Symbol:CD164  
NCBI Official Synonym Symbols:DFNA66; MGC-24; MUC-24; MGC-24v; endolyn  
NCBI Protein Information:sialomucin core protein 24
UniProt Protein Name:Sialomucin core protein 24
UniProt Synonym Protein Names:Endolyn; Multi-glycosylated core protein 24; MGC-24; MGC-24v; CD_antigen: CD164
Protein Family:CD164 sialomucin-like 2 protein
UniProt Gene Name:CD164  

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