Anti-EPB41L1 Antibody (CAB18361)

Antibody Name:	Anti-EPB41L1 Antibody
Antibody SKU:	CAB18361
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Mouse
Host Species:	Rabbit
Immunogen:	Recombinant protein of human EPB41L1.

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Mouse
Positive Samples:

Immunogen:	Recombinant protein of human EPB41L1.
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	Email for sequence
Gene ID:	2036
Uniprot:	Q9H4G0
Cellular Location:
Calculated MW:
Observed MW:	Refer to figures

Synonyms:	4.1N, MRD11, EPB41L1
Background:

UniProt Protein Function:	EPB41L1: May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases. Defects in EPB41L1 are the cause of mental retardation autosomal dominant type 11 (MRD11). Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 20q11.2-q12 Cellular Component: cytoskeleton; extrinsic to membrane; plasma membrane; cytosol Molecular Function:actin binding; structural molecule activity Biological Process: synaptic transmission; cortical actin cytoskeleton organization and biogenesis Disease: Mental Retardation, Autosomal Dominant 11
NCBI Summary:	Erythrocyte membrane protein band 4.1 (EPB41) is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane. The protein encoded by this gene is a neuronally-enriched protein that is structurally similar to EPB41. The encoded protein binds and stabilizes D2 and D3 dopamine receptors at the neuronal plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
UniProt Code:	Q9H4G0
NCBI GenInfo Identifier:	14916561
NCBI Gene ID:	2036
NCBI Accession:	Q9H4G0.2
UniProt Secondary Accession:	Q9H4G0,O15046, Q4VXM6, Q4VXM7, Q4VXM8, Q4VXN4, Q6ZT61 Q8IUU7, Q96CV5, Q96L65,
UniProt Related Accession:	Q9H4G0
Molecular Weight:	78,831 Da
NCBI Full Name:	Band 4.1-like protein 1
NCBI Synonym Full Names:	erythrocyte membrane protein band 4.1-like 1
NCBI Official Symbol:	EPB41L1
NCBI Official Synonym Symbols:	4.1N; MRD11
NCBI Protein Information:	band 4.1-like protein 1; neuronal protein 4.1; neuron-type nonerythroid protein 4.1
UniProt Protein Name:	Band 4.1-like protein 1
UniProt Synonym Protein Names:	Neuronal protein 4.1; 4.1N
Protein Family:	Band 4.1-like protein
UniProt Gene Name:	EPB41L1
UniProt Entry Name:	E41L1_HUMAN

ELISA Kits

Human EPB41L1 (Band 4.1-like protein 1) ELISA Kit (HUFI04427)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)