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Anti-MIOX Antibody (CAB17287)

SKU:
CAB17287
Product Type:
Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology
€129 - €259
Frequently bought together:

Description

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Antibody Name:Anti-MIOX Antibody
Antibody SKU:CAB17287
Antibody Size:20uL, 50 uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-431 of human MIOX (NP_001002036.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-431 of human MIOX (NP_001002036.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:APLA SSCA GACG TSFP DGLT PEGT QASG DKDI PAIN QGLI LEET PESS FLIE GDII RPSP FRLL SATS NKWP MGGS GVVE VPFL LSSK YDEP SRQV ILEA LAEF ERST CIRF VTYQ DQRD FISI IPMY GCFS SVGR SGGM QVVS LAPT CLQK GRGI VLHE LMHV LGFW HEHT RADR DRYI RVNW NEIL PGFE INFI KSQS SNML TPYD YSSV MHYG RLAF SRRG LPTI TPLW APSV HIGQ RWNL SASD ITRV LKLY GCSP SGPR PRGR GSHA HSTG RSPA PASL SLQR LLEA LSAE SRSP DPSG SSAG GQPV PAGP GESP HGWE SPAL KKLS AEAS ARQP QTLA SSPR SRPG AGAP GVAQ EQSW LAGV STKP TVPS SEAG IQPV PVQG SPAL PGGC VPRN HFKG MSED
Gene ID:431705
Uniprot:Q6HA08
Cellular Location:
Calculated MW:45kDa
Observed MW:Refer to figures
Synonyms:ASTL, SAS1B, MIOX
Background:
UniProt Protein Function:ASTL: Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding. Belongs to the peptidase M12A family.
UniProt Protein Details:

Protein type:EC 3.4.-.-; Protease

Chromosomal Location of Human Ortholog: 2q11.1

Cellular Component: transport vesicle; cytoplasm; plasma membrane

Molecular Function:peptidase activity; zinc ion binding; metalloendopeptidase activity

Biological Process: fertilization; proteolysis; cell adhesion

UniProt Code:Q6HA08
NCBI GenInfo Identifier:157502169
NCBI Gene ID:431705
NCBI Accession:NP_001002036.3
UniProt Secondary Accession:Q6HA08,Q3KNT0,
UniProt Related Accession:Q6HA08
Molecular Weight:45,936 Da
NCBI Full Name:astacin-like metalloendopeptidase
NCBI Synonym Full Names:astacin-like metallo-endopeptidase (M12 family)
NCBI Official Symbol:ASTL  
NCBI Official Synonym Symbols:SAS1B  
NCBI Protein Information:astacin-like metalloendopeptidase; ovastacin; oocyte astacin; sperm acrosomal SLLP1 binding; astacin-like metalloendopeptidase (M12 family)
UniProt Protein Name:Astacin-like metalloendopeptidase
UniProt Synonym Protein Names:Oocyte astacin; Ovastacin
Protein Family:Astacin-like metalloendopeptidase
UniProt Gene Name:ASTL  
UniProt Entry Name:ASTL_HUMAN

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