Anti-BCO2 Antibody (CAB5034)
- SKU:
- CAB5034
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- BCO2
- B-DIOX-II
- BCDO2
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Product Name: | BCO2 Rabbit pAb |
| Product Code: | CAB5034 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | BCO2, B-DIOX-II, BCDO2 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-410 of human BCO2 (NP_001243327.1). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SGC-7901, LO2, 293T, Hela, U-87MG, Mouse liver, Rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-410 of human BCO2 (NP_001243327.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | KAAG FSYK VIRV PPEK VDLG ETIH GVQV ICSI ASTE KGKP SYYH SFGM TRNY IIFI EQPL KMNL WKIA TSKI RGKA FSDG ISWE PQCN TRFH VVEK RTGQ LLPG RYYS KPFV TFHQ INAF EDQG CVII DLCC QDNG RTLE VYQL QNLR KAGE GLDQ VHNS AAKS FPRR FVLP LNVS LNAP EGDN LSPL SYTS ASAV KQAD GTIW CSHE NLHQ EDLE KEGG IEFP QIYY DRFS GKKY HFFY G |
| Gene ID: | 83875 |
| Uniprot: | Q9BYV7 |
| Cellular Location: | Mitochondrion |
| Calculated MW: | 53kDa/57kDa/60kDa/61kDa/65kDa |
| Observed MW: | 65kDa |
| UniProt Protein Function: | BCDO2: Asymmetrically cleaves beta-carotene at the 9',10' double bond resulting in the formation of beta-apo-10'-carotenal and beta-ionone. Besides beta-carotene, lycopene is also oxidatively cleaved. The apocarotenals formed by this enzyme may be the precursors for the biosynthesis of retinoic acid or exert unknown physiological effects. Belongs to the carotenoid oxygenase family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 1.13.11.71; Oxidoreductase Chromosomal Location of Human Ortholog: 11q23.1 Cellular Component: intracellular; mitochondrial matrix; mitochondrion Molecular Function:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Biological Process: carotene catabolic process; carotene metabolic process; carotenoid metabolic process; regulation of mitochondrial membrane potential; retinoid metabolic process |
| NCBI Summary: | This gene encodes an enzyme which oxidizes carotenoids such as beta-carotene during the biosynthesis of vitamin A. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
| UniProt Code: | Q9BYV7 |
| NCBI GenInfo Identifier: | 308153680 |
| NCBI Gene ID: | 83875 |
| NCBI Accession: | Q9BYV7.5 |
| UniProt Secondary Accession: | Q9BYV7,Q8IUS0, Q96JC8, Q96JY5, B0YIX5, B4DNC3, E9PBI8 E9PJJ1, |
| UniProt Related Accession: | Q9BYV7 |
| Molecular Weight: | 53,630 Da |
| NCBI Full Name: | Beta,beta-carotene 9',10'-oxygenase |
| NCBI Synonym Full Names: | beta-carotene oxygenase 2 |
| NCBI Official Symbol: | BCO2Â Â |
| NCBI Official Synonym Symbols: | BCDO2; B-DIOX-IIÂ Â |
| NCBI Protein Information: | beta,beta-carotene 9',10'-oxygenase |
| UniProt Protein Name: | Beta,beta-carotene 9',10'-oxygenase |
| UniProt Synonym Protein Names: | B-diox-II; Beta-carotene dioxygenase 2 |
| Protein Family: | Beta,beta-carotene 9',10'-oxygenase |
| UniProt Gene Name: | BCO2Â Â |
| UniProt Entry Name: | BCDO2_HUMAN |
Related Products
Human Anti-Apolipoprotein Antibody / AAHA ELISA Kit
€599
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
€599
Mouse ACCPA / anti-cyclic citrullinated peptide antibody ELISA Kit
€649
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
€599
Mouse ANA(Anti-nuclear Antibody) ELISA Kit
€599