null

Anti-SEMA5A Antibody (CAB14817)

SKU:
CAB14817
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology
€129 - €359
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-SEMA5A Antibody
Antibody SKU:CAB14817
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 330-500 of human SEMA5A (NP_003957.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 330-500 of human SEMA5A (NP_003957.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:AFSG PFKY QENS RSAW LPYP NPNP HFQC GTVD QGLY VNLT ERNL QDAQ KFIL MHEV VQPV TTVP SFME DNSR FSHV AVDV VQGR EALV HIIY LATD YGTI KKVR VPLN QTSS SCLL EEIE LFPE RRRE PIRS LQIL HSQS VLFV GLRE HVVK IPLK RCQF YRTR STCI GAQ
Gene ID:9037
Uniprot:Q13591
Cellular Location:Membrane, Single-pass type I membrane protein
Calculated MW:120kDa
Observed MW:150kDa
Synonyms:SEMA5A, SEMAF, semF
Background:This gene belongs to the semaphorin gene family that encodes membrane proteins containing a semaphorin domain and several thrombospondin type-1 repeats. Members of this family are involved in axonal guidance during neural development. This gene has been implicated as an autism susceptibility gene.
UniProt Protein Function:SEMA5A: a single-pass type I membrane protein that may act as positive axonal guidance cues.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 5p15.2

Cellular Component: integral to membrane; membrane; plasma membrane

Molecular Function:chemorepellent activity; heparan sulfate proteoglycan binding; semaphorin receptor binding; syndecan binding

Biological Process: axonal fasciculation; blood vessel endothelial cell proliferation during sprouting angiogenesis; cell adhesion; cell-cell signaling; diencephalon development; negative regulation of axon extension involved in axon guidance; negative regulation of cell adhesion; nervous system development; neural crest cell migration; positive chemotaxis; positive regulation of actin filament depolymerization; positive regulation of angiogenesis; positive regulation of axon extension involved in axon guidance; positive regulation of cell migration; positive regulation of endothelial cell proliferation; positive regulation of protein kinase B signaling cascade

NCBI Summary:This gene belongs to the semaphorin gene family that encodes membrane proteins containing a semaphorin domain and several thrombospondin type-1 repeats. Members of this family are involved in axonal guidance during neural development. This gene has been implicated as an autism susceptibility gene.[provided by RefSeq, Jan 2010]
UniProt Code:Q13591
NCBI GenInfo Identifier:109939725
NCBI Gene ID:9037
NCBI Accession:Q13591.3
UniProt Secondary Accession:Q13591,O60408, Q1RLL9, D3DTC6,
UniProt Related Accession:Q13591
Molecular Weight:120,615 Da
NCBI Full Name:Semaphorin-5A
NCBI Synonym Full Names:semaphorin 5A
NCBI Official Symbol:SEMA5A  
NCBI Official Synonym Symbols:semF; SEMAF  
NCBI Protein Information:semaphorin-5A
UniProt Protein Name:Semaphorin-5A
UniProt Synonym Protein Names:Semaphorin-F; Sema F
Protein Family:Semaphorin
UniProt Gene Name:SEMA5A  
UniProt Entry Name:SEM5A_HUMAN
Anti-SEMA5A Antibody (CAB14817)Western blot analysis of extracts of mouse liver, using SEMA5A antibody (CAB14817) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 3min.

Related Products