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CD155/PVR Monoclonal Antibody

SKU:
CAB23084
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
IHC
€139
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Description

Product Name:CD155/PVR Monoclonal Antibody
Product Code:CAB23084
Reactivity:Human
Applications:Western blotting, Immunohistochemistry
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC59175
Reactivity:Human
Tested Applications:WB, IHC-P, ELISA
Key Applications:Western blotting, Immunohistochemistry
Recommended Dilution:WB 1:1000-1:5000, IHC-P 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:A549
Cellular Location:Cell membrane, Secreted

The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 21-343 of human CD155/PVR (NP_006496.4).
Sequence:WPPPG TGDVV VQAPT QVPGF LGDSV TLPCY LQVPN MEVTH VSQLT WARHG ESGSM AVFHQ TQGPS YSESK RLEFV AARLG AELRN ASLRM FGLRV EDEGN YTCLF VTFPQ GSRSV DIWLR VLAKP QNTAE VQKVQ LTGEP VPMAR CVSTG GRPPA QITWH SDLGG MPNTS QVPGF LSGTV TVTSL WILVP SSQVD GKNVT CKVEH ESFEK PQLLT VNLTV YYPPE VSISG YDNNW YLGQN EATLT CDARS NPEPT GYNWS TTMGP LPPFA VAQGA QLLIR PVDKP INTTL ICNVT NALGA RQAEL TVQVK EGPPS EHSGI SRN
Synonyms:PVS, HVED, CD155, NECL5, TAGE4, Necl-5
Calculated MW:45kDa
Observed MW:70-80kDa

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