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ABCA1 Monoclonal Antibody (CAB21976)

SKU:
CAB21976
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
IF
€139 - €529
Frequently bought together:

Description

Product Name:ABCA1 Monoclonal Antibody
Product Code:CAB21976
Reactivity:Human, Mouse, Rat
Applications:Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC54239
Reactivity:Human, Mouse, Rat
Tested Applications:IF/ICC, ELISA
Key Applications:Immunofluorescence
Recommended Dilution:IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Cellular Location:Membrane, Multi-pass membrane protein

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1170-1350 of human ABCA1 (NP_005493.2).
Sequence:DHESD TLTID VSAIS NLIRK HVSEA RLVED IGHEL TYVLP YEAAK EGAFV ELFHE IDDRL SDLGI SSYGI SETTL EEIFL KVAEE SGVDA ETSDG TLPAR RNRRA FGDKQ SCLRP FTEDD AADPN DSDID PESRE TDLLS GMDGK GSYQV KGWKL TQQQF VALLW KRLLI ARRSR KGFFA Q
Synonyms:TGD, ABC1, CERP, ABC-1, HDLDT1, HPALP1, HDLCQTL13
Calculated MW:254kDa
Observed MW:Refer to figures

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