AGR3 Antibody (PACO15351)
- SKU:
- PACO15351
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | AGR3 Antibody (PACO15351) |
| Antibody SKU: | PACO15351 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:15-1:50 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human AGR3 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15351(AGR3 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: x200). |
 | Gel: 15%SDS-PAGE, Lysate: 40 μg, Lane 1-2: MCF7 cells, human colon tissue, Primary antibody: PACO15351(AGR3 Antibody) at dilution 1/150, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO15351(AGR3 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Anterior gradient protein 3 homolog is a protein that in humans is encoded by the AGR3 gene. The deduced 166-amino acid, protein has an N-terminal signal sequence. Fluorescence-tagged BCMP11 localized in secretory or endosome-like organelles in transfected breast carcinoma cell lines. Immunohistochemical analysis showed that expression of BCMP11 was restricted in normal tissues, with significant staining of only the epithelial lining of colonic mucosa. However, BCMP11 was detected in 43 of 58 (74%) breast cancer tissues tested, but not in normal breast ductal epithelial cells. In cancerous epithelial cells, BCMP11 localized to the cytoplasm. |
| Synonyms: | Anterior gradient 3 homolog (Xenopus laevis) |
| UniProt Protein Function: | AGR3: Belongs to the AGR family.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 7p21.1Cellular Component: extracellular regionMolecular Function: protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8TD06 |
| NCBI GenInfo Identifier: | 28827801 |
| NCBI Gene ID: | 155465 |
| NCBI Accession: | NP_789783.1 |
| UniProt Secondary Accession: | Q8TD06,A4D120 |
| UniProt Related Accession: | Q8TD06 |
| Molecular Weight: | 19,171 Da |
| NCBI Full Name: | anterior gradient protein 3 homolog |
| NCBI Synonym Full Names: | anterior gradient 3 homolog (Xenopus laevis) |
| NCBI Official Symbol: | AGR3Â Â |
| NCBI Official Synonym Symbols: | AG3; HAG3; hAG-3; BCMP11; PDIA18Â Â |
| NCBI Protein Information: | anterior gradient protein 3 homolog; AG-3; anterior gradient homolog 3; breast cancer membrane protein 11; protein disulfide isomerase family A, member 18 |
| UniProt Protein Name: | Anterior gradient protein 3 homolog |
| UniProt Synonym Protein Names: | Breast cancer membrane protein 11 |
| Protein Family: | Anterior gradient protein |
| UniProt Gene Name: | AGR3Â Â |
| UniProt Entry Name: | AGR3_HUMAN |
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