BMP8A Antibody (PACO23394)
- SKU:
- PACO23394
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | BMP8A Antibody (PACO23394) |
| Antibody SKU: | PACO23394 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IF:1:100-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from C-terminal of human BMP8A. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from COLO cells, using BMP8A antibody. |
 | Immunofluorescence analysis of A549 cells, using BMP8A antibody. |
| Background: | Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis By similarity. Signaling protein involved in regulation of thermogenesis and energy balance. Proposed to increase the peripheral response of brown adipose tissue (BAT) to adrenergic stimulation while acting centrally in the hypothalamus to increase sympathetic output to BAT. |
| Synonyms: | Bone morphogenetic protein 8A [Precursor]; BMP-8A; |
| UniProt Protein Function: | BMP8A: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. Belongs to the TGF-beta family.Protein type: Cytokine; Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 1p34.3Cellular Component: extracellular spaceMolecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor bindingBiological Process: BMP signaling pathway; regulation of apoptosis; ossification; diet induced thermogenesis; regulation of MAPKKK cascade; cartilage development; cell development; growth; negative regulation of insulin secretion |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q7Z5Y6 |
| NCBI GenInfo Identifier: | 145611428 |
| NCBI Gene ID: | 353500 |
| NCBI Accession: | NP_861525.2 |
| UniProt Secondary Accession: | Q7Z5Y6,Q5T3A5 |
| UniProt Related Accession: | Q7Z5Y6 |
| Molecular Weight: | 44,798 Da |
| NCBI Full Name: | bone morphogenetic protein 8A |
| NCBI Synonym Full Names: | bone morphogenetic protein 8a |
| NCBI Official Symbol: | BMP8AÂ Â |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | bone morphogenetic protein 8A; BMP-8A |
| UniProt Protein Name: | Bone morphogenetic protein 8A |
| UniProt Synonym Protein Names: | |
| Protein Family: | Bone morphogenetic protein |
| UniProt Gene Name: | BMP8AÂ Â |
| UniProt Entry Name: | BMP8A_HUMAN |
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