BRS3 Antibody (PACO19363)
- SKU:
- PACO19363
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | BRS3 Antibody (PACO19363) |
| Antibody SKU: | PACO19363 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide of human BRS3 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO19363(BRS3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19363(BRS3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | The protein encoded by this gene is a G protein-coupled membrane receptor that binds bombesin-like peptides. This binding results in activation of a phosphatidylinositol-calcium second messenger system, with physiological effects including regulation of metabolic rate, glucose metabolism, and hypertension. |
| Synonyms: | bombesin-like receptor 3 |
| UniProt Protein Function: | BRS3: Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integralChromosomal Location of Human Ortholog: Xq26.3Cellular Component: neuron projection; cell soma; integral to membrane; plasma membraneMolecular Function: bombesin receptor activityBiological Process: regulation of blood pressure; bombesin receptor signaling pathway; glucose metabolic process; adult feeding behavior |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a G protein-coupled membrane receptor that binds bombesin-like peptides. This binding results in activation of a phosphatidylinositol-calcium second messenger system, with physiological effects including regulation of metabolic rate, glucose metabolism, and hypertension. [provided by RefSeq, Sep 2011] |
| UniProt Code: | P32247 |
| NCBI GenInfo Identifier: | 416726 |
| NCBI Gene ID: | 680 |
| NCBI Accession: | P32247.1 |
| UniProt Secondary Accession: | P32247 |
| UniProt Related Accession: | P32247 |
| Molecular Weight: | 44,411 Da |
| NCBI Full Name: | Bombesin receptor subtype-3 |
| NCBI Synonym Full Names: | bombesin-like receptor 3 |
| NCBI Official Symbol: | BRS3Â Â |
| NCBI Official Synonym Symbols: | BB3Â Â |
| NCBI Protein Information: | bombesin receptor subtype-3; BRS-3; G-protein coupled receptor; bombesin receptor subtype 3 |
| UniProt Protein Name: | Bombesin receptor subtype-3 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Bombesin receptor |
| UniProt Gene Name: | BRS3Â Â |
| UniProt Entry Name: | BRS3_HUMAN |
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