HIV-1 gp41/120 Recombinant Protein (RPPB5577)
- SKU:
- RPPB5577
- Product Type:
- Recombinant Protein
- Species:
- Viral
Description
| Product Name: | HIV-1 gp41/120 Recombinant Protein |
| Product Code: | RPPB5577 |
| Size: | 0.5mg |
| Species: | HIV-1 |
| Target: | gp41/120 |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless clear solution. |
| Formulation: | 150mM NaCl, 25mM sodium phosphate pH-8, 50% glycerol and 150mM imidazole. |
| Stability: | HIV-1 gp41/120 although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
Human immunodeficiency virus (HIV) is a retrovirus that can lead to a condition in which the immune system begins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: firstly, direct viral killing of infected cells; secondly, increased rates of apoptosis in infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are charact
HIV-1 gp41-gp120 is a non-glycosylated polypeptide chain fused to 6xHis Tag.
