HTLV-1 Envelope Recombinant Protein (CPRT5605)

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Data SheetMSDS

HTLV-1 Envelope Recombinant Protein

Name:HTLV-1 Envelope
Introduction:Human T–lymphotropic virus (HTLV) is a human, single–stranded RNA retrovirus that causes T–cell leukemia and T–cell lymphoma. The virus activates a subset of T–helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN–gamma and TNF–alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL–4, IL–5, IL–10 and IL–13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invadingorganisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies).
Description:The E.Coli derived recombinant protein contains the C– terminus of gp46 and most of p21E of HTLV–1. This non–fusion, E. coli–derived protein, starts from HTLV–1 env. Amino acid 165, and is endingin amino acid 440, Mw 27 kDa.
Pack size:0.5mg
Physical Appearance:Sterile filtered colorless solution.
Formulation:10mM Na–PO4 pH 6.0, 0.1% SDS and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2–4 weeks. Store, frozen at –20°C for longer periods of time. For longterm storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze–thaw cycles.
Purity:HTLV–1 Envelope protein is >95% pure as determined by 10% PAGE (coomassie staining) and RP–HPLC.
Amino Acid Sequence:N/A
Biological Activity:N/A
Usage:Assay Genie’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Additional Information

Product type:
Recombinant Protein
Host Species:
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