Human Uroporphyrinogen III Synthase (CPRT2416)

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SKU:
CPRT2416
€278

Description

Recombinant Protein DatasheetAntibody MSDS

UROS Human Enzyme

Name:UROS Human
Synonyms:Uroporphyrinogen-III synthase, UROIIIS, UROS, Hydroxymethylbilane hydrolyase [cyclizing], Uroporphyrinogen-III cosynthase.
Introduction:Uroporphyrinogen III synthase (UROS) is an enzyme involved in the 4th step of porphyrin metabolism and in the conversion of hydroxymethyl bilane into uroporphyrinogen III. Defects in the UROS protein can cause molecular lesions which lead to the autosomal recessive Gunther disease, otherwise known as congenital erythropoietic porphyria (CEP).
Description:UROS produced in E.Coli is a single, non–glycosylated polypeptide chain containing 285 amino acids (1–265 a.a.) and having a molecular mass of 30.7kDa.UROS is fused to a 20 amino acid His–tag at N–terminus & purified by proprietary chromatographic techniques.
Source:Escherichia Coli.
Pack size:25µg
Physical Appearance:Sterile filtered colorless solution.
Formulation:UROS protein solution (1mg/ml) containing 20mM Tris–HCl buffer (pH8.0), 10% glycerol and 0.1M NaCl.
Solubility:N/A
Stability:UROS Human Recombinant although stable at 4°C for 1 week, should be stored below –18°C. Please prevent freeze thaw cycles.
Purity:Greater than 95.0% as determined by SDS–PAGE.
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MKVLLLKDAK EDDCGQDPYI RELGLYGLEA TLIPVLSFEF LSLPSFSEKL SHPEDYGGLI FTSPRAVEAA ELCLEQNNKT EVWERSLKEK WNAKSVYVVgNATASLVSKI GLDTEGETCgNAEKLAEYIC SRESSALPLL FPCGNLKREI LPKALKDKGI AMESITVYQT VAHPGIQGNL NSYYSQQGVP ASITFFSPSgLTYSLKHIQE LSGDNIDQIK FAAIGPTTAR ALAAQGLPVS CTAESPTPQA LATGIRKALQ PHGCC.
Biological Activity:N/A
Usage:Assay Genie’s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Uniprot:P10746
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Additional Information

Product type:
Enzyme
Reactivity:
Human
Host Species:
E.Coli
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