Description
ZWILCH Human Recombinant Protein
Name: | ZWILCH Human |
Synonyms: | hZwilch, KNTC1AP, Protein zwilch homolog, ZWILCH. |
Introduction: | Zwilch Kinetochore Protein which is also known as ZWILCH is a part of the ZWILCH family. ZWILCH is a vital part of the mitotic checkpoint. ZWILCH prevents the cells from exitingmitosis prematurely. ZWILCH is also necessary for the assembly of the dyneindynactin and MAD1–MAD2 complexes onto kinetochores. |
Description: | ZWILCH Human Recombinant produced in E.Coli is a single, non–glycosylated polypeptide chain containing 614 amino acids (1–591 a.a) and having a molecular mass of 69.6kDa. ZWILCH is fused to a 23 amino acid His–tag at N–terminus & purified by proprietary chromatographic techniques. |
Source: | Escherichia Coli. |
Pack size: | 10µg |
Physical Appearance: | Sterile Filtered colorless solution. |
Formulation: | ZWILCH protein solution (0.25mg/ml) containing 20mM Tris–HCl buffer (pH 8.0), 0.1M NaCl, 20% glycerol and 1mM DTT. |
Solubility: | N/A |
Stability: | Store at 4°C if entire vial will be used within 2–4 weeks. Store, frozen at –20°C for longer periods of time. For longterm storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze–thaw cycles. |
Purity: | Greater than 85.0% as determined by SDS–PAGE. |
Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMWERLNC AAEDFYSRLL QKFNEEKKGI RKDPFLYEAD VQVQLISKGQ PNPLKNILNE NDIVFIVEKV PLEKEETSHI EELQSEETAI SDFSTGENVgPLALPVGKAR QLIGLYTMAH NPNMTHLKIN LPVTALPPLW VRCDSSDPEgTCWLGAELIT TNNSITGIVL YVVSCKADKN YSVNLENLKN LHKKRHHLST VTSKGFAQYE LFKSSALDDT ITASQTAIAL DISWSPVDEI LQIPPLSSTA TLNIKVESGE PRGPLNHLYR ELKFLLVLAD GLRTGVTEWL EPLEAKSAVE LVQEFLNDLN KLDGFGDSTK KDTEVETLKH DTAAVDRSVK RLFKVRSDLD FAEQLWCKMS SSVISYQDLV KCFTLIIQSL QRGDIQPWLH SGSNSLLSKL IHQSYHGTMD TVSLSGTIPV QMLLEIGLDK LKKDYISFFI GQELASLNHL EYFIAPSVDI QEQVYRVQKL HHILEILVSC MPFIKSQHEL LFSLTQICIK YYKQNPLDEQ HIFQLPVRPT AVKNLYQSEK PQKWRVEIYS GQKKIKTVWQ LSDSSPIDHL NFHKPDFSEL TLNGSLEERI FFTNMVTCSQ VHFK. |
Biological Activity: | N/A |
Usage: | Assay Genie’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
Uniprot: | Q9H900 |
Additional Information
Product type: |
Recombinant Protein |
Reactivity: |
Human |
Host Species: |
E.Coli |