Anti-KCNK17 Antibody (PACO16578)

Antibody Name:	KCNK17 Antibody (PACO16578)
Antibody SKU:	PACO16578
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:100-1:300
Species Reactivity:	Human
Immunogen:	Fusion protein of human KCNK17

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO16578(KCNK17 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).
	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: LO2 cells, Primary antibody: PACO16578(KCNK17 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds.
	The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO16578(KCNK17 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).

Background:	The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is activated at alkaline pH. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms:	potassium channel, subfamily K, member 17

UniProt Protein Function:	KCNK17: Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents. Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 6p21.2Cellular Component: integral component of plasma membrane; plasma membraneMolecular Function: potassium channel activity; potassium ion leak channel activity; voltage-gated ion channel activityBiological Process: potassium ion transport; stabilization of membrane potential
UniProt Protein Details:
NCBI Summary:	The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is activated at alkaline pH. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
UniProt Code:	Q96T54
NCBI GenInfo Identifier:	205361107
NCBI Gene ID:	89822
NCBI Accession:	NP_001128583.1
UniProt Secondary Accession:	Q96T54,Q5TCF4, Q8TAW4, Q9BXD1, Q9H592, E9PB46
UniProt Related Accession:	Q96T54
Molecular Weight:	29,972 Da
NCBI Full Name:	potassium channel subfamily K member 17 isoform 2
NCBI Synonym Full Names:	potassium two pore domain channel subfamily K member 17
NCBI Official Symbol:	KCNK17
NCBI Official Synonym Symbols:	TALK2; TASK4; TALK-2; TASK-4; K2p17.1
NCBI Protein Information:	potassium channel subfamily K member 17
UniProt Protein Name:	Potassium channel subfamily K member 17
UniProt Synonym Protein Names:	2P domain potassium channel Talk-2; Acid-sensitive potassium channel protein TASK-4; TWIK-related acid-sensitive K(+) channel 4; TWIK-related alkaline pH-activated K(+) channel 2; TALK-2
Protein Family:	Potassium channel subfamily
UniProt Gene Name:	KCNK17
UniProt Entry Name:

Antibodies

KCNK17 Antibody (PACO05656)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)