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NKX2-5 Polyclonal Antibody (CAB21992)

SKU:
CAB21992
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€129 - €359
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:NKX2-5 Polyclonal Antibody
SKU:CAB21992
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-137 of human NKX2-5 (NP_004378.1).
Sequence:QRSL AAAG ELSA RLEA TLAP SSCM LAAF KPEA YAGP EAAA PGLP ELRA ELGR APSP AKCA SAFP AAPA FYPR AYSD PDPA KDPR AEKK ELCA LQKA VELE KTEA DNAE RPRA RR
Tested Applications:WB ELISA
Recommended Dilution:WB,1:100 - 1:500
Synonyms:CSX; CSX1; VSD3; CHNG5; HLHS2; NKX2E; NKX2.5; NKX4-1; NKX2-5
Positive Sample:Mouse heart,Rat heart
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:35kDa
Observed MW:30-42kDa

This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:1482
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates, using NKX2-5 Rabbit pAb (CAB21992) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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