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Phospho-AMPKa1-T183 + AMPKa2-T172 Monoclonal Antibody

SKU:
CABP1345
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€139 - €609
Frequently bought together:

Description

Product Name:Phospho-AMPKa1-T183 + AMPKa2-T172 Monoclonal Antibody
Product Code:CABP1345
Reactivity:Mouse
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC53386
Reactivity:Mouse
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:C2C12+oligomycin
Cellular Location:Apical plasma membrane, Cytoplasm, Cytosol, Nuclear speck, Nucleoplasm, nucleus
Customer Validation:WB(Gallus gallus)

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Immunogen:A synthetic phosphorylated peptide around T183 of human AMPKa1 (NP_006242.5).
Sequence:LRTSC
Synonyms:AMPKa1/AMPKa2
Calculated MW:64kDa/65kDa/62kDa
Observed MW:62kDa

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