PTMA Antibody (PACO18982)
- SKU:
- PACO18982
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | PTMA Antibody (PACO18982) |
| Antibody SKU: | PACO18982 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide of human PTMA |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18982(PTMA Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO18982(PTMA Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Prothymosin α may mediate immune function by conferring resistance to certain opportunistic infections and as oncogenes contributing to cell proliferation and invasion in BC. Silencing of these gene significantly inhibited cell proliferation and invasion, and increased apoptosis in BC cells. Immunohistochemistry showed that PTMA expression levels were significantly higher in BC compared to normal bladder epitheliums. |
| Synonyms: | prothymosin, alpha |
| UniProt Protein Function: | PTMA: Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections. Belongs to the pro/parathymosin family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Nuclear receptor co-regulator Chromosomal Location of Human Ortholog: 2q37.1 Cellular Component: cytoplasm; nucleoplasm; nucleus Molecular Function:protein binding Biological Process: transcription, DNA-dependent |
| UniProt Code: | P06454 |
| NCBI GenInfo Identifier: | 135834 |
| NCBI Gene ID: | 5757 |
| NCBI Accession: | P06454.2 |
| UniProt Secondary Accession: | P06454,Q15249, Q15592, |
| UniProt Related Accession: | P06454 |
| Molecular Weight: | 12,074 Da |
| NCBI Full Name: | Prothymosin alpha |
| NCBI Synonym Full Names: | prothymosin, alpha |
| NCBI Official Symbol: | PTMAÂ Â |
| NCBI Official Synonym Symbols: | TMSAÂ Â |
| NCBI Protein Information: | prothymosin alpha |
| UniProt Protein Name: | Prothymosin alpha |
| Protein Family: | Prothymosin |
| UniProt Gene Name: | PTMAÂ Â |
| UniProt Entry Name: | PTMA_HUMAN |
| Antibodies | ELISA Kits |
| Anti-PTMA Antibody (CAB1956) | Human PTMA / Prothymosin alpha ELISA Kit |
| PTMA Antibody (PACO11581) | Human Prothymosin alpha (PTMA) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
