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Human Semaphorin 4D/SEMA4D Recombinant Protein (RPES4305)

SKU:
RPES4305
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Growth Factors & Cytokines
$265
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Description

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Human Semaphorin 4D/SEMA4D Recombinant Protein

Semaphorin-4D is also known as A8;BB18; GR3; CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain; 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells; regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2; which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.