SLC16A12 Antibody (PACO55186)
- SKU:
- PACO55186
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | SLC16A12 Antibody (PACO55186) |
| Antibody SKU: | PACO55186 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Monocarboxylate transporter 12 protein (431-486AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Jurkat whole cell lysate, 293 whole cell lysate, Hela whole cell lysate, HepG2 whole cell lysate. All lanes: SLC16A12 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 54 kDa. Observed band size: 54 kDa. |
 | Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO55186 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO55186 at dilution of 1:100. |
| Background: | Proton-linked monocarboxylate transporter that mediates creatine transport across the plasma membrane. |
| Synonyms: | Monocarboxylate transporter 12 (MCT 12) (Creatine transporter 2) (CRT2) (Solute carrier family 16 member 12), SLC16A12, MCT12 |
| UniProt Protein Function: | SLC16A12: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates. Defects in SLC16A12 are a cause of cataract juvenile with microcornea and glucosuria (CJMG). Renal glucosuria is defined by elevated glucose level in the urine without hyperglycemia and without evidence of morphological renal anomalies. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.Protein type: Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass; TransporterChromosomal Location of Human Ortholog: 10q23.31Cellular Component: integral to plasma membraneMolecular Function: creatine transporter activity; lactate transmembrane transporter activity; symporter activityDisease: Cataract, Juvenile, With Microcornea And Glucosuria |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a transmembrane transporter that likely plays a role in monocarboxylic acid transport. A mutation in this gene has been associated with juvenile cataracts with microcornea and renal glucosuria. [provided by RefSeq, Mar 2010] |
| UniProt Code: | Q6ZSM3 |
| NCBI GenInfo Identifier: | 147704293 |
| NCBI Gene ID: | 387700 |
| NCBI Accession: | Q6ZSM3.2 |
| UniProt Secondary Accession: | Q6ZSM3,Q5M9M9, Q5T7J2, Q6ZV76 |
| UniProt Related Accession: | Q6ZSM3 |
| Molecular Weight: | 53,075 Da |
| NCBI Full Name: | Monocarboxylate transporter 12 |
| NCBI Synonym Full Names: | solute carrier family 16 member 12 |
| NCBI Official Symbol: | SLC16A12Â Â |
| NCBI Official Synonym Symbols: | CJMG; CRT2; MCT12Â Â |
| NCBI Protein Information: | monocarboxylate transporter 12 |
| UniProt Protein Name: | Monocarboxylate transporter 12 |
| UniProt Synonym Protein Names: | Creatine transporter 2 |
| Protein Family: | Monocarboxylate transporter |
| UniProt Gene Name: | SLC16A12Â Â |
| UniProt Entry Name: | MOT12_HUMAN |
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