null

SQSTM1/p62 Polyclonal Antibody (CAB21702)

SKU:
CAB21702
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
IHC
IF
IP
$167 - $635
Frequently bought together:

Description

Product Name:SQSTM1/p62 Polyclonal Antibody
Product Code:CAB21702
Reactivity:Human, Mouse, Rat
Applications:Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Mouse, Rat
Tested Applications:WB, IHC-P, IF/ICC, IP, ELISA
Key Applications:Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation
Recommended Dilution:WB 1:2000-1:4000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200, IP 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:293T, HeLa, L929, PC-12
Cellular Location:Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Late endosome, Lysosome, Nucleus, P-body, autophagosome

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 340-440 of human SQSTM1/p62. (NP_003891.1).
Sequence:HLSSK EVDPS TGELQ SLQMP ESEGP SSLDP SQEGP TGLKE AALYP HLPPE ADPRL IESLS QMLSM GFSDE GGWLT RLLQT KNYDI GAALD TIQYS KHPPP L
Synonyms:p60, p62, A170, DMRV, OSIL, PDB3, ZIP3, p62B, NADGP, FTDALS3
Calculated MW:48kDa
Observed MW:62kDa

Related Products