| UniProt Protein Function: | SSX2IP: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E- cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Cell adhesionChromosomal Location of Human Ortholog: 1p22.3Cellular Component: protein complex; cell-cell adherens junction; leading edge; nucleusMolecular Function: protein domain specific binding; protein bindingBiological Process: regulation of Rac protein signal transduction; centrosome organization and biogenesis; cilium biogenesis; cell adhesion |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Oct 2009] |
| UniProt Code: | Q9Y2D8 |
| NCBI GenInfo Identifier: | 261878552 |
| NCBI Gene ID: | 117178 |
| NCBI Accession: | NP_001159889.1 |
| UniProt Secondary Accession: | Q9Y2D8,Q6P2P8, Q6ULS1, Q7L168, Q9UIX0, A8K8W0, B4DFE3 D3DT13, J3KR02 |
| UniProt Related Accession: | Q9Y2D8 |
| Molecular Weight: | 68,274 Da |
| NCBI Full Name: | afadin- and alpha-actinin-binding protein isoform 1 |
| NCBI Synonym Full Names: | synovial sarcoma, X breakpoint 2 interacting protein |
| NCBI Official Symbol: | SSX2IPÂ Â |
| NCBI Official Synonym Symbols: | ADIPÂ Â |
| NCBI Protein Information: | afadin- and alpha-actinin-binding protein; SSX2-interacting protein; afadin DIL domain-interacting protein |
| UniProt Protein Name: | Afadin- and alpha-actinin-binding protein |
| UniProt Synonym Protein Names: | Afadin DIL domain-interacting protein; SSX2-interacting protein |
| Protein Family: | Afadin- and alpha-actinin-binding protein |
| UniProt Gene Name: | SSX2IPÂ Â |
| UniProt Entry Name: | ADIP_HUMAN |
