14-3-3 zeta/YWHAZ Monoclonal Antibody
- SKU:
- CAB24006
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- IF
Frequently bought together:
Description
| Product Name: | 14-3-3 zeta/YWHAZ Monoclonal Antibody |
| Product Code: | CAB24006 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62843 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:2000-1:10000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, HeLa, NIH/3T3, Mouse brain, PC-12, Rat brain |
| Cellular Location: | Cytoplasm, Melanosome |
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 145-245of human YWHAZ (NP_002267.2). |
| Sequence: | SQQAY QEAFE ISKKE MQPTH PIRLG LALNF SVFYY EILNS PEKAC SLAKT AFDEA IAELD TLSEE SYKDS TLIMQ LLRDN LTLWT SDTQG DEAEA GEGGE N |
| Synonyms: | HEL4, YWHAD, KCIP-1, HEL-S-3, POPCHAS, HEL-S-93, 14-3-3-zeta |
| Calculated MW: | 19kDa/28kDa |
| Observed MW: | 30kDa |
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