Anti-CERS4 Antibody (PACO23283)

Antibody Name:	CERS4 Antibody (PACO23283)
Antibody SKU:	PACO23283
Size:	100ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100
Species Reactivity:	Human, Mouse
Immunogen:	Synthesized peptide derived from internal of human LASS4.

Form:	Liquid
Storage Buffer:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Western blot analysis of extracts from COLO cells, Jurkat cells and HUVEC cells, using LASS4 antibody.
	Immunohistochemistry analysis of paraffin-embedded human brain tissue using LASS4 antibody.

Background:	May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner By similarity.
Synonyms:	LAG1 longevity assurance homolog 4; LASS4;

UniProt Protein Function:	Lass4: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner.Protein type: Membrane protein, multi-pass; Membrane protein, integral; DNA-bindingChromosomal Location of Human Ortholog: 19p13.2Cellular Component: endoplasmic reticulum; endoplasmic reticulum membraneMolecular Function: sphingosine N-acyltransferase activityBiological Process: ceramide biosynthetic process; sphingolipid biosynthetic process
UniProt Protein Details:
NCBI Summary:
UniProt Code:	Q9HA82
NCBI GenInfo Identifier:	296434561
NCBI Gene ID:	79603
NCBI Accession:	Q9HA82.2
UniProt Secondary Accession:	Q9HA82,D6W665
UniProt Related Accession:	Q9HA82
Molecular Weight:	46,399 Da
NCBI Full Name:	Ceramide synthase 4
NCBI Synonym Full Names:	ceramide synthase 4
NCBI Official Symbol:	CERS4
NCBI Official Synonym Symbols:	Trh1; LASS4
NCBI Protein Information:	ceramide synthase 4
UniProt Protein Name:	Ceramide synthase 4
UniProt Synonym Protein Names:	LAG1 longevity assurance homolog 4
Protein Family:	Ceramide synthase
UniProt Gene Name:	CERS4
UniProt Entry Name:	CERS4_HUMAN

Antibodies

Secondary Antibody