GOSR1 Antibody (PACO13473)
- SKU:
- PACO13473
- Product Type:
- Antibody
- Host Species:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Size:
- 100 µg
- Target:
- GOSR1
Frequently bought together:
Description
| Antibody Name: | GOSR1 Antibody |
| Antibody SKU: | PACO13473 |
| Size: | 50 µg |
| Target Name: | GOSR1 |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human GS28 |
| Immunogen Species: | Homo sapiens (Human) |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Storage: | Store at -20°C or -80°C. Avoid repeated freeze. |
| Isotype: | IgG |
| Synonyms: | GOSR1; GS28; Golgi SNAP receptor complex member 1; 28 kDa Golgi SNARE protein; 28 kDa cis-Golgi SNARE p28; GOS-28 |
| UniProt Code: | O95249 |
| Target Background Function: | Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi. |
| Subcellular Location: | Golgi apparatus membrane; Single-pass type IV membrane protein. |
| Protein Families: | GOSR1 family |
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