null

Anti-GOSR1 Antibody (CAB4316)

SKU:
CAB4316
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
  • Cell Biology Antibodies 9 Anti-GOSR1 Antibody CAB4316
  • Cell Biology Antibodies 9 Anti-GOSR1 Antibody CAB4316
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-GOSR1 Antibody
Antibody SKU:CAB4316
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human GOSR1 (NP_004862.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:Mouse testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human GOSR1 (NP_004862.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAAG TSSY WEDL RKQA RQLE NELD LKLV SFSK LCTS YSHS STRD GRRD RYSS DTTP LLNG SSQD RMFE TMAI EIEQ LLAR LTGV NDKM AEYT NSAG VPSL NAAL MHTL QRHR DIL
Gene ID:9527
Uniprot:O95249
Cellular Location:Golgi apparatus membrane, Single-pass type IV membrane protein
Calculated MW:21kDa/28kDa
Observed MW:29kDa
Synonyms:GOSR1, GOLIM2, GOS-28, GOS28, GOS28/P28, GS28, P28
Background:This gene encodes a trafficking membrane protein which transports proteins among the endoplasmic reticulum and the Golgi and between Golgi compartments. This protein is considered an essential component of the Golgi SNAP receptor (SNARE) complex. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
UniProt Protein Function:GOSR1: a single-pass type IV Golgi membrane protein. Enriched on vesicular components at the terminal rims of the Golgi. Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. Identified in a unique SNARE complex composed of the Golgi SNAREs GOSR2, STX5, GABARAPL2 and YKT6.
UniProt Protein Details:

Protein type:Vesicle; Membrane protein, integral; Autophagy

Chromosomal Location of Human Ortholog: 17q11

Cellular Component: Golgi membrane; SNARE complex; Golgi apparatus; cis-Golgi network; membrane; integral to membrane

Molecular Function:SNAP receptor activity

Biological Process: intra-Golgi vesicle-mediated transport; protein transport; ER to Golgi vesicle-mediated transport; retrograde transport, endosome to Golgi

NCBI Summary:This gene encodes a trafficking membrane protein which transports proteins among the endoplasmic reticulum and the Golgi and between Golgi compartments. This protein is considered an essential component of the Golgi SNAP receptor (SNARE) complex. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:O95249
NCBI GenInfo Identifier:12643659
NCBI Gene ID:9527
NCBI Accession:O95249.1
UniProt Secondary Accession:O95249,O75392, J3KST5,
UniProt Related Accession:O95249
Molecular Weight:250
NCBI Full Name:Golgi SNAP receptor complex member 1
NCBI Synonym Full Names:golgi SNAP receptor complex member 1
NCBI Official Symbol:GOSR1  
NCBI Official Synonym Symbols:P28; GS28; GOS28; GOLIM2; GOS-28; GOS28/P28  
NCBI Protein Information:Golgi SNAP receptor complex member 1; cis-golgi SNARE; Golgi SNARE 28 kDa; 28 kDa Golgi SNARE protein; 28 kDa cis-Golgi SNARE p28; golgi integral membrane protein 2
UniProt Protein Name:Golgi SNAP receptor complex member 1
UniProt Synonym Protein Names:28 kDa Golgi SNARE protein; 28 kDa cis-Golgi SNARE p28; GOS-28
UniProt Gene Name:GOSR1  
UniProt Entry Name:GOSR1_HUMAN
Anti-GOSR1 Antibody (CAB4316)Western blot analysis of extracts of mouse testis, using GOSR1 antibody (CAB4316) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 15s.
Anti-GOSR1 Antibody (CAB4316)Immunofluorescence analysis of U2OS cells using GOSR1 antibody (CAB4316) at dilution of 1:100. Blue: DAPI for nuclear staining.

Related Products