Human CD43 Recombinant Protein (hFc Tag) (HDPT0476)

SKU:
HDPT0476
€550

Description

Human CD43 Recombinant Protein (hFc Tag)

Description:This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]
Product name:Human CD43 Recombinant Protein (hFc Tag)
Synonyms:CD43; GALGP; GPL115; LSN
Type:protein
Size:50 µg
Name:CD43
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:Contact Technical Support
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:CD43 (Ser20-R253)+hFc(GLU99-ALA330)
Gene ID:
Uniprot:P16150
Molecular Weight:51.26 kDa
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Additional Information

Product Type:
Recombinant Protein
Host Species:
HEK293
Reactivity:
Human
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