PMM1 Antibody (PACO29022)
- SKU:
- PACO29022
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | PMM1 Antibody (PACO29022) |
| Antibody SKU: | PACO29022 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Phosphomannomutase 1 protein (2-262AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: PMM1 antibody at 2µg/ml Lane 1: HepG2 whole cell lysate Lane 2: NIH/3T3 whole cell lysate Lane 3: 293T whole cell lysate Lane 4: Mouse brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 30 kDa Observed band size: 30 kDa . |
 | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO29022 at dilution of 1:100. |
| Background: | Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain. |
| Synonyms: | Phosphomannomutase 1 (PMM 1) (EC 5.4.2.8) (PMMH-22), PMM1, PMMH22 |
| UniProt Protein Function: | PMM1: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain. Belongs to the eukaryotic PMM family.Protein type: Carbohydrate Metabolism - amino sugar and nucleotide sugar; Carbohydrate Metabolism - fructose and mannose; EC 5.4.2.8; IsomeraseChromosomal Location of Human Ortholog: 22q13.2Cellular Component: cytosolMolecular Function: phosphomannomutase activity; protein bindingBiological Process: GDP-mannose biosynthetic process; mannose metabolic process; protein amino acid N-linked glycosylation; protein targeting to ER |
| UniProt Protein Details: | |
| NCBI Summary: | Phosphomannomutase catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q92871 |
| NCBI GenInfo Identifier: | 194097356 |
| NCBI Gene ID: | 5372 |
| NCBI Accession: | NP_002667.2 |
| UniProt Secondary Accession: | Q92871,Q92586, A8K003 |
| UniProt Related Accession: | Q92871 |
| Molecular Weight: | 29,747 Da |
| NCBI Full Name: | phosphomannomutase 1 |
| NCBI Synonym Full Names: | phosphomannomutase 1 |
| NCBI Official Symbol: | PMM1Â Â |
| NCBI Official Synonym Symbols: | Sec53Â Â |
| NCBI Protein Information: | phosphomannomutase 1 |
| UniProt Protein Name: | Phosphomannomutase 1 |
| UniProt Synonym Protein Names: | PMMH-22 |
| Protein Family: | |
| UniProt Gene Name: | PMM1Â Â |
| UniProt Entry Name: | PMM1_HUMAN |
| Antibodies |
| PMM1 Antibody (PACO11317) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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