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Anti-IGFBP2 Antibody (CAB9018)

SKU:
CAB9018
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
IBP2
IGF-BP53
Research Area:
Developmental Biology
$167 - $503
Frequently bought together:

Description

Product Name:IGFBP2 Rabbit mAb
Product Code:CAB9018
Size:20uL, 50uL, 100uL
Synonyms:IBP2, IGF-BP53
Applications:WB, IHC
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human IGFBP2
Applications:WB, IHC
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human
Positive Samples:HepG2, PC-3
Immunogen:A synthesized peptide derived from human IGFBP2
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:3485
Uniprot:P18065
Calculated MW:35kDa
Observed MW:35KDa
UniProt Protein Function:IGFBP2: Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Binds IGF2 more than IGF1.
UniProt Protein Details:

Protein type:Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: extracellular space; apical plasma membrane; extracellular region; cytoplasmic vesicle

Molecular Function:protein binding; insulin-like growth factor I binding; insulin-like growth factor II binding

Biological Process: response to drug; regulation of insulin-like growth factor receptor signaling pathway; response to retinoic acid; response to lithium ion; response to glucocorticoid stimulus; female pregnancy; positive regulation of activated T cell proliferation; signal transduction; response to estradiol stimulus; cellular response to hormone stimulus; cellular protein metabolic process; response to mechanical stimulus; regulation of cell growth; response to nutrient; aging

UniProt Code:P18065
NCBI GenInfo Identifier:290457647
NCBI Gene ID:3485
NCBI Accession:P18065.2
UniProt Secondary Accession:P18065,Q14619, Q9UCL3,
UniProt Related Accession:P18065
Molecular Weight:34,814 Da
NCBI Full Name:Insulin-like growth factor-binding protein 2
NCBI Synonym Full Names:insulin-like growth factor binding protein 2, 36kDa
NCBI Official Symbol:IGFBP2  
NCBI Official Synonym Symbols:IBP2; IGF-BP53  
NCBI Protein Information:insulin-like growth factor-binding protein 2; IBP-2; IGFBP-2; IGF-binding protein 2
UniProt Protein Name:Insulin-like growth factor-binding protein 2
Protein Family:Insulin-like growth factor-binding protein
UniProt Gene Name:IGFBP2  
UniProt Entry Name:IBP2_HUMAN

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