CD99 Antibody (PACO21219)
- SKU:
- PACO21219
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | CD99 Antibody (PACO21219) |
| Antibody SKU: | PACO21219 |
| Size: | 100ul(100ug) |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant protein of human CD99 |
| Form: | Liquid |
| Storage Buffer: | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Purification Method: | Affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts of various cell lines, using CD99 antibody. |
| Background: | The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Synonyms: | CD99; HBA71; MIC2; MIC2X; MIC2Y; MSK5X; CD99 antigen; 12E7; E2 antigen; Protein MIC2; T-cell surface glycoprotein E2 |
| UniProt Protein Function: | Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes. |
| NCBI Summary: | The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016] |
| UniProt Code: | P14209 |
| NCBI GenInfo Identifier: | 119049 |
| NCBI Gene ID: | 4267 |
| NCBI Accession: | P14209.1 |
| UniProt Secondary Accession: | P14209,O00518, Q6ICV7, A6NIW1, |
| UniProt Related Accession: | P14209 |
| Molecular Weight: | 17,128 Da |
| NCBI Full Name: | CD99 antigen |
| NCBI Synonym Full Names: | CD99 molecule (Xg blood group) |
| NCBI Official Symbol: | CD99 |
| NCBI Official Synonym Symbols: | MIC2; HBA71; MIC2X; MIC2Y; MSK5X |
| NCBI Protein Information: | CD99 antigen |
| UniProt Protein Name: | CD99 antigen |
| UniProt Synonym Protein Names: | 12E7; E2 antigen; Protein MIC2; T-cell surface glycoprotein E2; CD_antigen: CD99 |
| Protein Family: | CD99 antigen |
| UniProt Gene Name: | CD99 |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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