| UniProt Protein Function: | EPS8L1: Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. Belongs to the EPS8 family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 19q13.42 Cellular Component: cytoplasm; protein complex Molecular Function:actin binding; protein binding; Rac guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity; T cell receptor binding Biological Process: regulation of Rho protein signal transduction; Rho protein signal transduction |
| NCBI Summary: | This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8TE68 |
| NCBI GenInfo Identifier: | 296439363 |
| NCBI Gene ID: | 54869 |
| NCBI Accession: | Q8TE68.3 |
| UniProt Secondary Accession: | Q8TE68,Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0 |
| UniProt Related Accession: | Q8TE68 |
| Molecular Weight: | 55,807 Da |
| NCBI Full Name: | Epidermal growth factor receptor kinase substrate 8-like protein 1 |
| NCBI Synonym Full Names: | EPS8 like 1 |
| NCBI Official Symbol: | EPS8L1Â Â |
| NCBI Official Synonym Symbols: | DRC3; EPS8R1; PP10566Â Â |
| NCBI Protein Information: | epidermal growth factor receptor kinase substrate 8-like protein 1 |
| UniProt Protein Name: | Epidermal growth factor receptor kinase substrate 8-like protein 1 |
| UniProt Synonym Protein Names: | Epidermal growth factor receptor pathway substrate 8-related protein 1; EPS8-related protein 1 |
| Protein Family: | Epidermal growth factor receptor kinase substrate 8-like protein |
| UniProt Gene Name: | EPS8L1Â Â |
| UniProt Entry Name: | ES8L1_HUMAN |
