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Anti-FPR1 Antibody (CAB20455)

SKU:
CAB20455
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
FPR
FMLP
€139 - €419
Frequently bought together:

Description

Product Name:FPR1 Rabbit pAb
Product Code:CAB20455
Size:50uL, 100uL
Synonyms:FPR, FMLP
Applications:WB, IHC
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant protein of human FPR1.
Applications:WB, IHC
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human
Immunogen:Recombinant protein of human FPR1.
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:2357
Uniprot:P21462
Calculated MW:38kDa
Observed MW:Refer to figures
UniProt Protein Function:FPR1: High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Motility/polarity/chemotaxis; Receptor, GPCR Chromosomal Location of Human Ortholog: 19q13.4 Cellular Component: endosome; plasma membrane Molecular Function: N-formyl peptide receptor activity; protein binding; receptor activity Biological Process: activation of MAPK activity; cell motility; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); nitric oxide mediated signal transduction; signal transduction
UniProt Protein Details:
NCBI Summary:This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010]
UniProt Code:P21462
NCBI GenInfo Identifier:288558848
NCBI Gene ID:2357
NCBI Accession:P21462.3
UniProt Secondary Accession:P21462,Q14939, Q7Z6A4, Q86U52, Q9NS48
UniProt Related Accession:P21462
Molecular Weight:38,446 Da
NCBI Full Name:fMet-Leu-Phe receptor
NCBI Synonym Full Names:formyl peptide receptor 1
NCBI Official Symbol:FPR1  
NCBI Official Synonym Symbols:FPR; FMLP  
NCBI Protein Information:fMet-Leu-Phe receptor
UniProt Protein Name:fMet-Leu-Phe receptor
UniProt Synonym Protein Names:N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
Protein Family:FK506-binding protein
UniProt Gene Name:FPR1  
UniProt Entry Name:FPR1_HUMAN

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