Human Heat Shock 22 kDa Protein-8, His Tag Recombinant Protein (CPRT5257)

SKU:
CPRT5257
€278

Description

Data SheetMSDS

HSPB8 Human, His Recombinant Protein

Name:HSPB8 Human, His
Synonyms:HSPB8, H11, HMN2, CMT2L, DHMN2, E2IG1, HMN2A, HSP22, Heat shock protein beta-8, Alpha-crystallin C chain, Small stress protein-like protein HSP22, E2-induced gene 1 protein, Protein kinase H11, CRYAC.
Introduction:HSPB8 is part of the superfamily of small heat–shock proteins containing a conservative alpha–crystallin domain at the C–terminal part of the molecule. HSPB8 is induced by estrogen in estrogen receptor–positive breast cancer cells. HSPB8 protein functions as a chaperone in association with BAG3, a stimulator of macroautophagy. HSPB8 participates in the regulation of cell proliferation, apoptosis, and carcinogenesis. Mutations in HSPB8 gene have been related with different neuromuscular diseases, includingCharcot–Marie–Tooth disease.
Description:HSPB8 Human Recombinant produced in E.Coli is a single, non–glycosylated polypeptide chain containing 216 amino acids (1–196 a.a.) and having a molecular mass of 23.7kDa. The HSPB8 is fused to a 20 amino acid His tag at N–terminus and purified by conventional chromatography.
Source:Escherichia Coli.
Pack size:10µg
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The HSPB8 protein solution contains 20mM Tris–HCl pH–8, 100mM NaCl, and 10% glycerol.
Solubility:N/A
Stability:Store at 4°C if entire vial will be used within 2–4 weeks. Store, frozen at –20°C for longer periods of time. For longterm storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze–thaw cycles.
Purity:Greater than 95.0% as determined by SDS–PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MADGQMPFSC HYPSRLRRDP FRDSPLSSRL LDDGFGMDPF PDDLTASWPD WALPRLSSAW PGTLRSGMVP RGPTATARFgVPAEGRTPPP FPGEPWKVCV NVHSFKPEEL MVKTKDGYVE VSGKHEEKQQ EGGIVSKNFT KKIQLPAEVD PVTVFASLSP EGLLIIEAPQ VPPYSTFGES SFNNELPQDS QEVTCT.
Biological Activity:N/A
Usage:Assay Genie’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Uniprot:Q9UJY1
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Additional Information

Product type:
Recombinant Protein
Reactivity:
Human
Host Species:
E.Coli
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