MPP6 Antibody (PACO20845)
- SKU:
- PACO20845
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | MPP6 Antibody (PACO20845) |
| Antibody SKU: | PACO20845 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:30-1:150 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human MPP6 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20845(MPP6 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20845(MPP6 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]). |
| Synonyms: | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| UniProt Protein Function: | VAM-1: a membrane-associated of the MAGUK family. Interacts with Lin7, which localizes to postsynaptic densities of neurons and epithelial cell-cell junctions. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Adaptor/scaffold Chromosomal Location of Human Ortholog: 7p15 Molecular Function:protein binding |
| NCBI Summary: | Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9NZW5 |
| NCBI GenInfo Identifier: | 42560556 |
| NCBI Gene ID: | 51678 |
| NCBI Accession: | Q9NZW5.2 |
| UniProt Secondary Accession: | Q9NZW5,Q9H0E1, A4D157, |
| UniProt Related Accession: | Q9NZW5 |
| Molecular Weight: | 61,117 Da |
| NCBI Full Name: | MAGUK p55 subfamily member 6 |
| NCBI Synonym Full Names: | membrane palmitoylated protein 6 |
| NCBI Official Symbol: | MPP6Â Â |
| NCBI Official Synonym Symbols: | VAM1; p55T; PALS2; VAM-1Â Â |
| NCBI Protein Information: | MAGUK p55 subfamily member 6 |
| UniProt Protein Name: | MAGUK p55 subfamily member 6 |
| UniProt Synonym Protein Names: | Veli-associated MAGUK 1; VAM-1 |
| Protein Family: | MAGUK p55 subfamily |
| UniProt Gene Name: | MPP6Â Â |
| UniProt Entry Name: | MPP6_HUMAN |
| Antibodies | ELISA Kits |
| Anti-MPP6 Antibody (CAB10509) | Human VAM1 / MPP6 / MAGUK p55 subfamily member 6 ELISA Kit |
| MPP6 Antibody (PACO10557) | Human MAGUK p55 subfamily member 6 (MPP6) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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