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Phospho-HDAC4-S246 + HDAC5-S259 + HDAC9-S220 Monoclonal Antibody

SKU:
CABP1394
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
IHC
€139 - €609
Frequently bought together:

Description

Product Name:Phospho-HDAC4-S246 + HDAC5-S259 + HDAC9-S220 Monoclonal Antibody
Product Code:CABP1394
Reactivity:Human, Mouse, Rat
Applications:Western blotting, Immunohistochemistry
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC56536
Reactivity:Human, Mouse, Rat
Tested Applications:WB, IHC-P, ELISA
Key Applications:Western blotting, Immunohistochemistry
Recommended Dilution:WB 1:500-1:1000, IHC-P 1:100-1:500
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:293T
Cellular Location:cytoplasm, cytosol, histone deacetylase complex, nuclear speck, nucleoplasm, nucleus

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]

Immunogen:A phospho synthetic peptide corresponding to residues surrounding S246&S259&S220 of Human HDAC4&HDAC5-S259&HDAC9.
Sequence:Email for sequence
Synonyms:HDAC4/HDAC5/HDAC9
Calculated MW:57-65kDa/97-122kDa
Observed MW:124kDa/140kDa

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