Human BLK Recombinant Protein (RPES1464)

Product type:
Recombinant Protein
Host species:


ELISA Kit Technical Manual

Recombinant Human BLK Protein (His Tag)

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Background:Tyrosine-Protein Kinase Blk (BLK) contains one protein kinase domain, one SH2 domain and one SH3 domain. BLK is a non-receptor tyrosine kinase, which is involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulines and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor. Defects in BLK are a cause of maturity-onset diabetes of the young type 11 (MODY11).
Name:Recombinant Human BLK Protein (His Tag)
Assay Genie SKU:RPES1464
Synonyms:Tyrosine-Protein Kinase Blk; B Lymphocyte Kinase; p55-Blk; BLK;MODY11
Expression host:E.coli
Mol Mass:58.7 kDa
AP Mol Mass:58.7 kDa
Purity:> 85 % as determined by reducing SDS-PAGE.
Endotoxin:< 1.0 EU per µg as determined by the LAL method.
Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Formulation:Supplied as a 0.2 um filtered solution of 20mM Tris, 500mM NaCl, 1mM DTT, pH 7.4.
Reconstitution:Please refer to the printed manual for detailed information.