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Anti-BTBD1 Antibody (CAB15160)

SKU:
CAB15160
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology
€129 - €359
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Description

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Antibody Name:Anti-BTBD1 Antibody
Antibody SKU:CAB15160
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human BTBD1 (NP_079514.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human BTBD1 (NP_079514.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:CDGT ANTF RVMF KEPI EILP NVCY TACA TLKG PDSH YGTK GLKK VVHE TPAA SKTV FFFF SSPG NNNG TSIE DGQI PEII FYT
Gene ID:53339
Uniprot:Q9H0C5
Cellular Location:Cytoplasm, P-body
Calculated MW:42kDa/52kDa
Observed MW:Refer to figures
Synonyms:BTBD1, C15orf1, NS5ATP8
Background:The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms.
UniProt Protein Function:BTBD1: Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
UniProt Protein Details:

Protein type:Unknown function

Chromosomal Location of Human Ortholog: 15q24

Cellular Component: protein complex

Molecular Function:protein binding

NCBI Summary:The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
UniProt Code:Q9H0C5
NCBI GenInfo Identifier:20137477
NCBI Gene ID:53339
NCBI Accession:Q9H0C5.1
UniProt Secondary Accession:Q9H0C5,Q9BX71, Q9NWN4, A6NMI8,
UniProt Related Accession:Q9H0C5
Molecular Weight:42,117 Da
NCBI Full Name:BTB/POZ domain-containing protein 1
NCBI Synonym Full Names:BTB domain containing 1
NCBI Official Symbol:BTBD1  
NCBI Official Synonym Symbols:C15orf1; NS5ATP8  
NCBI Protein Information:BTB/POZ domain-containing protein 1
UniProt Protein Name:BTB/POZ domain-containing protein 1
UniProt Synonym Protein Names:Hepatitis C virus NS5A-transactivated protein 8; HCV NS5A-transactivated protein 8
UniProt Gene Name:BTBD1  
UniProt Entry Name:BTBD1_HUMAN

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