Anti-MRPL48 Antibody (CAB17449)

Antibody Name:	Anti-MRPL48 Antibody
Antibody SKU:	CAB17449
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant protein of human MRPL48.

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse, Rat
Positive Samples:

Immunogen:	Recombinant protein of human MRPL48.
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	Email for sequence
Gene ID:	51642
Uniprot:	Q96GC5
Cellular Location:
Calculated MW:
Observed MW:	Refer to figures

Synonyms:

L48MT, CGI-118, HSPC290, MRP-L48, MRPL48

Background:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene.

UniProt Protein Function:	MRPL48: Interacts with OXA1L.
UniProt Protein Details:	Protein type:Mitochondrial Chromosomal Location of Human Ortholog: 11q13.4 Cellular Component: mitochondrial inner membrane; mitochondrial ribosome Molecular Function:protein binding
NCBI Summary:	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016]
UniProt Code:	Q96GC5
NCBI GenInfo Identifier:	118573683
NCBI Gene ID:	51642
NCBI Accession:	Q96GC5.2
UniProt Secondary Accession:	Q96GC5,Q49AK7, Q4U2Q4, Q9P091, Q9Y5J0, B4DN34,
UniProt Related Accession:	Q96GC5
Molecular Weight:	21,749 Da
NCBI Full Name:	39S ribosomal protein L48, mitochondrial
NCBI Synonym Full Names:	mitochondrial ribosomal protein L48
NCBI Official Symbol:	MRPL48
NCBI Official Synonym Symbols:	L48MT; CGI-118; HSPC290; MRP-L48
NCBI Protein Information:	39S ribosomal protein L48, mitochondrial
UniProt Protein Name:	39S ribosomal protein L48, mitochondrial
Protein Family:	39S ribosomal protein
UniProt Gene Name:	MRPL48
UniProt Entry Name:	RM48_HUMAN

Antibodies

MRPL48 Antibody (PACO04560)

MRPL48 Antibody (PACO10592)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)