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Phospho-NF-κB2-S866/S870 Monoclonal Antibody

SKU:
CABP1391
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
IHC
€139 - €609
Frequently bought together:

Description

Product Name:Phospho-NF-κB2-S866/S870 Monoclonal Antibody
Product Code:CABP1391
Reactivity:Human, Mouse
Applications:Western blotting, Immunohistochemistry
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC57764
Reactivity:Human, Mouse
Tested Applications:WB, IHC-P, ELISA
Key Applications:Western blotting, Immunohistochemistry
Recommended Dilution:WB 1:1000-1:5000, IHC-P 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:NIH/3T3 TNF-α
Cellular Location:Cytoplasm, Nucleus

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.

Immunogen:A synthetic phosphorylated peptide around S866&S870 of human NF.
Sequence:Email for sequence
Synonyms:p52, p100, H2TF1, LYT10, CVID10, LYT-10, NF-kB2, p49/p100
Calculated MW:97kDa
Observed MW:110kDa

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