RBFOX3 Antibody (PACO58100)
- SKU:
- PACO58100
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | RBFOX3 Antibody (PACO58100) |
| Antibody SKU: | PACO58100 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human RNA binding protein fox-1 homolog 3 protein (1-101AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO58100 diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD). |
| Synonyms: | RNA binding protein fox-1 homolog 3 (Fox-1 homolog C) (Neuronal nuclei antigen) (NeuN antigen), RBFOX3 |
| UniProt Protein Function: | NeuN: RNA-binding protein that regulates alternative splicing events. |
| UniProt Protein Details: | Protein type:RNA splicing; RNA processing; DNA-binding Chromosomal Location of Human Ortholog: 17q25.3 Cellular Component: cytoplasm; perikaryon; nucleus Molecular Function:DNA binding; RNA binding; nucleotide binding Biological Process: RNA splicing; mRNA processing; regulation of alternative nuclear mRNA splicing, via spliceosome |
| UniProt Code: | A6NFN3 |
| NCBI GenInfo Identifier: | 322510139 |
| NCBI Gene ID: | |
| NCBI Accession: | A6NFN3.4 |
| Molecular Weight: | 46-55kDa |
| NCBI Full Name: | RNA binding protein fox-1 homolog 3 |
| UniProt Protein Name: | RNA binding protein fox-1 homolog 3 |
| UniProt Synonym Protein Names: | Fox-1 homolog C |
| UniProt Gene Name: | RBFOX3 |
| UniProt Entry Name: | RFOX3_HUMAN |
| Antibodies |
| Anti-NeuN Antibody (CAB0951)[KO Validated] |
| Anti-RBFOX3 Antibody (CAB15959) |
| Anti-RBFOX3 Antibody (CAB17261) |
| Anti-NeuN Antibody (CAB19086) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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