| Background: | Matrix metallopeptidase 9 (MMP-9) is an enzyme encoded by the MMP9 gene. This protein, which is produced by normal alveolar macrophages and granulocytes, can be activated by 4-aminophenylmercuric acetate and phorbol ester and up-regulated by ARHGEF4, SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. MMP-9 is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, angiogenesis, bone development, wound healing, cell migration, learning and memory, as well as in pathological processes, such as arthritis, intracerebral hemorrhage, and metastasis. |
| Name: | Recombinant Human MMP-9 Protein (His Tag) |
| Size: | 10µg |
| Assay Genie SKU: | RPES4168 |
| Synonyms: | Matrix metalloproteinase-9;92 kDa gelatinase;92 kDa type IV collagenase;Gelatinase B;MMP9;CLG4B;GELB;MANDP2 |
| Species: | Human |
| Expression host: | Human Cells |
| Sequence: | Ala19-Asp707 |
| Accession: | NP_004985.2 |
| Mol Mass: | 77.4 kDa |
| AP Mol Mass: | 90 kDa |
| Tag: | C-6His |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin: | < 1.0 EU per µg as determined by the LAL method. |
| Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Formulation: | Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 2mM CaCl2, 150mM NaCl, 0.05% Brij35(w/v), pH 7.5. |
| Reconstitution: | Please refer to the printed manual for detailed information. |
