Human POLD2 Recombinant Protein (RPES2482)
- SKU:
- RPES2482
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Epigenetics & Nuclear Signaling
Frequently bought together:
Description
system_update_altDatasheet
Human POLD2 Recombinant Protein
DNA Polymerase Delta Subunit 2 (POLD2) belongs to the DNA polymerase delta/II small subunit family. POLD2 can form a heterotetramer composed of subunits of 125 kDa, 50 kDa, 66 kDa and 12 kDa. POLD2 possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. POLD2 is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA).
| Product Name: | Human POLD2 Recombinant Protein (RPES2482) |
| Product Code: | RPES2482 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | DNA Polymerase Delta Subunit 2, DNA Polymerase Delta Subunit p50, POLD2 |
| Accession: | P49005 |
| Sequence: | Met 1-Pro469 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human DNA Polymerase Delta Subunit 2 is produced by our E.coli expression system and the target gene encoding Met1-Pro469 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 52.3 kDa |
| AP Mol Mass: | 56 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of PBS, 10% Glycerol, pH 7.4. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
