Anti-SLC6A12 Antibody (CAB10378)
- SKU:
- CAB10378
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Neuroscience
Frequently bought together:
Description
| Antibody Name: | Anti-SLC6A12 Antibody |
| Antibody SKU: | CAB10378 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 515-614 of human SLC6A12 (NP_003035.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | 293T |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 515-614 of human SLC6A12 (NP_003035.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | FSLS KYTP LKYN NVYV YPPW GYSI GWFL ALSS MVCV PLFV VITL LKTR GPFR KRLR QLIT PDSS LPQP KQHP CLDG SAGR NFGP SPTR EGLI AGEK ETHL |
| Gene ID: | 6539 |
| Uniprot: | P48065 |
| Cellular Location: | Membrane, Multi-pass membrane protein |
| Calculated MW: | 69kDa |
| Observed MW: | 69kDa |
| Synonyms: | SLC6A12, BGT-1, BGT1, GAT2 |
| Background: |
| UniProt Protein Function: | SLC6A12: Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family Chromosomal Location of Human Ortholog: 12p13.33 Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane Molecular Function:amino acid transmembrane transporter activity; protein binding; transporter activity Biological Process: amino acid transport; transport |
| UniProt Code: | P48065 |
| NCBI GenInfo Identifier: | 257050987 |
| NCBI Gene ID: | 6539 |
| NCBI Accession: | P48065.2 |
| UniProt Secondary Accession: | P48065,A0AV52, B2R992, D3DUN8, |
| UniProt Related Accession: | P48065 |
| Molecular Weight: | 69kDa |
| NCBI Full Name: | Sodium- and chloride-dependent betaine transporter |
| NCBI Synonym Full Names: | solute carrier family 6 member 12 |
| NCBI Official Symbol: | SLC6A12Â Â |
| NCBI Official Synonym Symbols: | BGT1; GAT2; BGT-1Â Â |
| NCBI Protein Information: | sodium- and chloride-dependent betaine transporter |
| UniProt Protein Name: | Sodium- and chloride-dependent betaine transporter |
| UniProt Synonym Protein Names: | BGT-1; Na(+)/Cl(-) betaine/GABA transporter; Solute carrier family 6 member 12 |
| UniProt Gene Name: | SLC6A12Â Â |
 | Western blot analysis of extracts of 293T cells, using SLC6A12 antibody (CAB10378) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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