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By Charlotte O'Donnell PhD A role for IL-33 in Barrier Function and Epithelial Wound Healing IL-33 is constitutively expressed by cells involved in the maintenance of mechanical barriers, including keratinocytes, lung and gut epithelial cells, fibroblasts and smooth muscle cells [1]. In these cells IL-33 is localized to the nucleus and mediates gene transcription. It is believed to maintain a quiescent state as it is onl …